Sclerosing Nevus with Pseudomelanomatous Features (Nevus with Regression-Like Fibrosis): Clinical and Dermoscopic Features of a Recently Characterized Histopathologic Entity
Sclerosing Nevus with Pseudomelanomatous Features (Nevus with Regression-Like Fibrosis): Clinical and Dermoscopic Features of a Recently Characterized Histopathologic Entity
复制标题
具有假性黑素瘤特征的硬化性痣（具有回归样纤维化的痣）：最近表征的组织病理学实体的临床和皮肤镜特征
作者：
G. Ferrara;C. M. Giorgio;I. Zalaudek;P. Broganelli;G. Pellacani;C. Tomasini;G. Argenziano
背景资料：硬化痣与假黑色素瘤的特点，否则，痣与退化样纤维化（NRLF）是组织病理学模拟退化黑色素瘤。目的：探讨一系列非自然性淋巴瘤（NRLF）的临床特点。研究方法：根据消退量、白色/蓝色区域的存在和7点检查表重新评价NRLF的皮肤镜图像。结果：对44例患者（男：女= 3.4：1;平均年龄：42岁）的46处病变进行了评价。从背部切除了37处病变，大部分来自肩胛区。所有病变均为皮肤镜下不典型病变，大量消退（43例>10%），白色和蓝色区域共存（41例）。根据7点检查表，25个病灶被标记为良性，可能是因为退化掩盖了其他皮肤镜检查的特点。结论：NRLF好发于背部凸面。更好地认识他们的临床病理特征，可以允许一个更保守的管理。
Background: Sclerosing nevi with pseudomelanomatous features or, else, nevi with regression-like fibrosis (NRLF) are histopathologic simulators of regressing melanoma. Objective: We aimed at evaluating the clinical features in a series of NRLF. Methods: Dermoscopic images of NRLF were re-evaluated according to the amount of regression, the presence of white/blue areas and the 7-point checklist. Results: Forty-six lesions from 44 patients (M:F = 3.4:1; mean age: 42 years) were evaluated. Thirty-seven lesions were excised from the back, mostly from the scapular area. All the lesions were dermoscopically atypical, with large amounts of regression (>10% in 43 cases) and with coexistence of white and blue areas (41 cases). According to the 7-point checklist, 25 lesions were labeled as benign, probably because regression obscured other dermoscopic features of atypia. Conclusion: NRLF are mostly found in the convex area of the back. A better recognition of their clinicopathologic features can allow a more conservative management.