Epidemiology of paediatric metabolic syndrome and type 2 diabetes mellitus.
Epidemiology of paediatric metabolic syndrome and type 2 diabetes mellitus.
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DOI：
10.3132/dvdr.2007.055
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发表时间：
2007-12-01
影响因子：
2.4
通讯作者：
Osganian, Stavroula K
中科院分区：
文献类型：
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作者：
De Ferranti, Sarah D;Osganian, Stavroula K
儿童肥胖症的流行是儿科代谢综合征增加的驱动力，这是一组与成人心血管疾病和2型糖尿病风险增加有关的异常。虽然对代谢综合征的儿科定义没有明确的共识，但这种综合征的患病率明显上升。患有代谢综合征的儿童在成年后患代谢综合征的风险增加。代谢综合征的晚期后果是2型糖尿病，越来越多地影响青少年。儿童代谢综合征和2型糖尿病的增加几乎肯定会导致年轻人相关并发症的增加，包括早期心血管疾病。这一流行病将在未来几十年内结出果实，给医疗保健系统带来进一步的压力，并可能导致发病率增加和后代寿命缩短。
The epidemic in childhood obesity is a driving force behind the increase in paediatric metabolic syndrome, a collection of abnormalities that is associated in adults with increased risk for cardiovascular disease and type 2 diabetes mellitus. Although there is no clear consensus about the paediatric definition for metabolic syndrome, the prevalence of this syndrome is clearly rising. Children with metabolic syndrome are at increased risk for metabolic syndrome in adulthood. A late consequence of metabolic syndrome is type 2 diabetes, which increasingly affects adolescents. The rise in metabolic syndrome and type 2 diabetes in children is almost sure to lead to an increase in associated complications in young adulthood, including early cardiovascular disease. This epidemic will bear fruit in forthcoming decades, putting further stress on the healthcare system and probably leading to increased morbidity and a shorter lifespan for future generations.