Preparation of an appropriate antigen extract for patch tests with garlic.
Preparation of an appropriate antigen extract for patch tests with garlic.
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制备适当的抗原提取物用于大蒜斑贴试验。
DOI：
10.1001/archderm.1979.04010020068025
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发表时间：
1979
影响因子：
--
通讯作者：
B. Guru
中科院分区：
文献类型：
--
作者：
J. Pasricha;B. Guru
在最近的一项研究中，大蒜（Allium sativum）被发现是家庭主妇指尖接触性皮炎的最常见原因。然而，用未稀释的大蒜汁进行的斑贴试验在几个对照对象中也呈阳性。虽然有人认为，对照组的贴片试验呈阳性，表明对大蒜有潜在的过敏反应，但仍进行了进一步的研究来证实这一结论。对象与方法对10例指尖接触性皮炎患者和35例未发生指尖接触性皮炎的对照组进行调查。对照组分为两类：(1)23人经常烹饪并接触生大蒜汁；(2)12人从未接触过大蒜。每个病例的诊断都是基于详细的病史、病变分布模式、斑贴试验、
In a recent study, 1 garlic ( Allium sativum ) was found to be the most frequent cause of contact dermatitis on the fingertips of housewives. However, patch tests with the undiluted juice of garlic were positive in several control subjects also. Although it was suggested that positive patch tests in the controls should indicate latent hypersensitivity to garlic, further studies were undertaken to substantiate the conclusions. Subjects and Methods Ten cases of patients having contact dermatitis on their fingertips and 35 controls with contact dermatitis due to some other agent, but with no dermatitis on their fingertips, were investigated. The controls were of two types: (1) 23 individuals who cooked routinely and were exposed to the juice of raw garlic and (2) 12 individuals who had never handled garlic. The diagnosis in each case was made on the basis of a detailed history, pattern of distribution of the lesions, patch tests,