Reasons for Undergoing CT During Childhood: Can CT-Exposed and CT-Naive Populations Be Compared?
Reasons for Undergoing CT During Childhood: Can CT-Exposed and CT-Naive Populations Be Compared?
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DOI：
10.1177/1559325820907011
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发表时间：
2020-01-01
期刊：
影响因子：
2.5
通讯作者：
Ozawa, Yoshiyuki
中科院分区：
文献类型：
--
作者：
Shibata, Shunsuke;Shibamoto, Yuta;Ozawa, Yoshiyuki
一些流行病学研究表明，在儿童时期接受计算机断层扫描（CT）检查的个体患癌症和其他肿瘤的风险增加;然而，接受CT检查的人群是否与未接受CT检查的人群具有可比性存在疑问。为了解决这个问题，我们调查了2013年763名0至19岁儿童接受CT的原因。他们的医疗记录进行了充分的评估和症状，基础条件，CT的原因，CT后的临床过程进行了调查。在763例患儿中，66.1%的患儿在首次检查后进行了重复CT检查，19.3%的患儿进行了8次及以上CT检查。在所有接受检查的儿童中，8.8%患有癌症，4.7%患有唐氏综合征、结节性硬化症和肝硬化等癌症易感性疾病。763例中仅11.4%的患儿因外伤而接受CT检查，32.2%的患儿存在各种先天性畸形。创伤率随CT检查频率的增加而降低。由于一般人群中先天性畸形的发生率低于2.5%，因此得出结论，接受CT的儿童人群与未接受CT的儿童人群完全不同。两组不应进行比较。
Several epidemiological studies suggested an increased risk of cancer and other tumors in individuals undergoing computed tomography (CT) examination during childhood; however, it was questioned whether the group undergoing CT was comparable to that not undergoing CT. To address this issue, we investigated the reasons for undergoing CT in 763 children aged 0 to 19 years in 2013. Their medical records were fully evaluated and symptoms, underlying conditions, reasons for CT, and clinical courses after CT were investigated. Among the 763 children, 66.1% underwent repeat CT after the first examination, and 19.3% underwent CT 8 times or more. Among all the examined children, 8.8% had cancer and 4.7% had cancer-prone conditions such as Down syndrome, tuberous sclerosis, and cirrhosis. Only 11.4% of the 763 children underwent CT because of trauma, and 32.2% of the children had some types of congenital anomaly. The rate of trauma decreased with an increase in the frequency of CT examinations. Since the incidence of congenital anomalies is below 2.5% in the general population, it was concluded that the population of children undergoing CT is completely different from that not undergoing CT. The 2 groups should not be compared.