Accurate energy compensation for intragastric and oral nutrients in lean males.
Accurate energy compensation for intragastric and oral nutrients in lean males.
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DOI：
10.1093/ajcn/61.4.754
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发表时间：
1995-04
期刊：
影响因子：
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通讯作者：
D. J. Shide;B. Caballero;R. Reidelberger;B. Rolls
中科院分区：
文献类型：
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作者：
D. J. Shide;B. Caballero;R. Reidelberger;B. Rolls
瘦削健康的男性接受了肠外或肠内注入纯脂肪或碳水化合物(2092kJ)或等渗盐水，以确定他们对自己选择的午餐和晚餐的食物摄入量和能量调节的影响。在第一项研究中，6名男性在早上接受3.5h的静脉输液，然后在输液结束后30min吃午饭，6h后吃晚餐。静脉输液中的能量差异没有得到补偿。在第二项研究中，6名男性接受了15分钟或3.5小时的灌胃。快速灌胃脂肪或碳水化合物和缓慢灌输脂肪显著减少了午餐的摄入量，而缓慢灌输碳水化合物则没有。在这两项研究中，受试者在2092-kJ酸奶预负荷2092-kJ后30分钟减少了午餐的摄入量，证明了他们对口服衍生能量的反应能力。这些结果支持在胃肠道中存在快速检测精瘦男性摄入的营养素或食物的能量含量的机制。
Lean healthy males received either parenteral or enteral infusions of pure fat or carbohydrate (2092 kJ), or isotonic saline, to determine their influences on food intake and energy regulation in self-selected lunch and dinner meals. In the first study, six males received intravenous infusions for 3.5 h in the morning, followed by lunch 30 min after the infusion ended and dinner 6 h later. No compensation was seen for energy differences in intravenous infusions. In the second study, six males received intragastric infusions for 15 min or 3.5 h. Rapid intragastric infusions of fat or carbohydrate and slow infusions of fat significantly reduced intake at lunch, whereas slow carbohydrate infusions did not. In both studies, subjects reduced intake at lunch 30 min after 2092-kJ yogurt preloads varying in fat and carbohydrate, demonstrating their ability to respond to orally derived energy. These results support the existence of mechanisms in the gastrointestinal tract for the rapid detection of the energy content of ingested nutrients or foods in lean males.