Incidence and cost of osteoporotic fractures in France during 2001. A methodological approach by the national hospital database
Incidence and cost of osteoporotic fractures in France during 2001. A methodological approach by the national hospital database
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DOI：
10.1007/s00198-005-2031-0
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发表时间：
2005-12-01
影响因子：
4
通讯作者：
Fardellone, P
中科院分区：
文献类型：
--
作者：
Maravic, M;Le Bihan, C;Fardellone, P
本研究的目的是描述2001年期间法国45岁以上男性和女性中三种外周“肱骨近端”骨折（肱骨和髋部近端、桡骨远端和/或尺骨远端）的住院发病率和住院费用。每次骨折住院时间均选自2001年法国国家医院数据库的数据集。根据最近一次法国人口普查（1999年），按年龄和性别对发病率（CI 95%）进行标准化。研究了发病率的年龄和地理差异的影响。对于每种骨折，我们根据2004年法国诊断相关组的费用清单（2004欧元）描述了住院次数、手术率和住院费用; 2001年登记了118，839例骨折（61%髋关节，28%桡骨远端和11%肱骨近端;性别比0.26）。在45岁以上的妇女和男子中，每10（6）名居民中的所有骨折发生率分别为7 567（7 519 - 7 615）和2 312（2 283 - 2 341）。无论骨折类型和性别，其发生率均显著增加。法国东部的骨折发生率高于西部，南部高于北部，无论女性骨折类型如何，男性骨折仅限于髋部骨折。在91%的髋部近端骨折、83%的桡骨远端骨折和53%的肱骨近端骨折中进行了外科手术。肱骨的平均住院费用为3，786欧元，桡骨为2，363至2，574欧元，髋关节为8，048至8，727欧元。使用法国国家医院的数据可以评价外周骨折的负担。骨折的发生率随着年龄的增长而增加，在女性中更常见。髋部骨折的发生率、手术率和住院费用较高，可作为骨质疏松症的一个指标，用于评估治疗策略。
The objective of this study was to describe the hospital incidence rate and the in-patient costs of three peripheral "osteoporotic" fractures (proximal humerus and hip, distal radius and/or ulna) in women and men aged over 45 in France during 2001. Each stay for fracture was selected from the dataset of the French national hospital database in 2001. The incidence rate (CI 95%) was standardized by age and gender according to the last census of the French population (1999). The effect of age and existence of geographical difference in incidence rates has been studied. For each fracture, we described the number of stays, rate of surgical procedure and in-patient costs according to the 2004 French list of cost per diagnosis-related group (2004 Euros); 118,839 fractures were registered during 2001 (61% hip, 28% distal radius and 11% proximal humerus; sex ratio 0.26). The incidence rate for all fracture was 7,567 (7,519-7,615) and 2,312 (2,283-2,341) for 10(6) inhabitants in women and men aged over 45 years, respectively. The incidence increased significantly whatever type of fracture and gender. There were more fracture incidents in the east of France compared to the west and in the south compared to the north, whatever type of fracture in women and only for hip fracture in men. Surgical procedures were performed in 91% of proximal hip fractures, 83% of distal radius fractures and 53% of proximal humerus fractures. The median in-patient costs were 3,786 Euros for the humerus, from 2,363 to 2,574 Euros for the radius and from 8,048 to 8,727 Euros for the hip. The evaluation of the burden of peripheral fractures is possible using national hospital data in France. The incidence of fractures increased with age and is more common in women. Hip fracture with its higher occurrence, rate of procedure and in-patient costs could be used as a marker of osteoporosis for evaluating strategies of management.