Prevalence of relative bradycardia in Orientia tsutsugamushi infection
Prevalence of relative bradycardia in Orientia tsutsugamushi infection
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DOI：
10.4269/ajtmh.2003.68.477
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发表时间：
2003-04-01
影响因子：
3.3
通讯作者：
Watt, G
中科院分区：
文献类型：
--
作者：
Aronoff, DM;Watt, G
我们调查了100例感染恙虫病东方体（恙虫病的病原体）的发热患者是否存在相对心动过缓，定义为心率增加< 10次/分钟/10 ℃。整个发热性恙虫病人群的中位心率反应为9.3次/分钟/℃，相对心动过缓的患病率为53%。相对心动过缓的发生与患者年龄或性别无关。相对心动过缓患者和正常发热脉搏增加患者的基础体温或发热体温中位数无差异。然而，相对心动过缓的发热患者在感染恢复后的静息脉率明显高于患病期间脉搏正常增加的患者。这些数据表明，相对心动过缓往往伴随着轻度感染O。恙虫病和基线心血管参数可能影响恙虫病发热心率反应。
We investigated 100 febrile patients infected with Orientia tsutsitgamushi (the etiologic agent of scrub typhus) for the presence of relative bradycardia, defined as in increase in heart rate of < 10 beats/minutes/1degreesC increase in temperature. The median heart rate response for the entire febrile scrub typhus population was 9.3 beats/minute/degreesC and the prevalence of relative bradycardia was 53%. The occurrence of relative bradycardia was independent of patient age or gender. There were no differences in median basal temperature or febrile temperature between those patients exhibiting relative bradycardia and those with a normal febrile pulse increase. However, febrile patients with relative bradycardia had a significantly higher resting pulse rate following recovery from infection than did patients who had a normal pulse increase during their illness. These data demonstrate that relative bradycardia frequently accompanies mild infection with O. tsutsugamushi and that baseline cardiovascular parameters may affect the febrile heart rate response to scrub typhus.