Transmuscular quadratus lumborum block versus oblique subcostal transversus abdominis plane block for analgesia in laparoscopic hysterectomy: a randomised single-blind trial.
Transmuscular quadratus lumborum block versus oblique subcostal transversus abdominis plane block for analgesia in laparoscopic hysterectomy: a randomised single-blind trial.
复制标题
经肌性腰方肌阻滞与斜肋下腹横肌平面阻滞用于腹腔镜子宫切除术镇痛：一项随机单盲试验
DOI：
10.1136/bmjopen-2020-043883
复制
发表时间：
2021-08-10
期刊：
影响因子：
2.9
通讯作者：
Shi K
中科院分区：
文献类型：
--
作者：
Huang L;Zheng L;Zhang J;Zhu X;Pan L;Zhang Y;Wang Q;Shi K
腰方肌(TQL)和斜肋下横腹肌平面(OSTAP)均可用于腹腔镜手术后的多模式镇痛。本研究的目的是比较TQL阻滞剂和Ostap阻滞剂在腹腔镜子宫切除术后的镇痛效果。前瞻性、单中心、随机、单盲试验。大学附属医院。年龄在18岁至65岁之间的患者行腹腔镜子宫切除术。患者按1：1比例随机分为两组，分别行双侧TQL阻滞或双侧Ostap阻滞，每侧均注入0.375%罗比卡因20 m L。主要的结果衡量标准是前24小时内的吗啡累积剂量。次要结果指标为术后各时间点的吗啡消耗量、从手术结束到首次需要吗啡的时间、内脏和切口疼痛强度的数值评定量表(NRS)评分以及不良事件的发生率。TQL组吗啡累积剂量显著低于OSTAP组(17.2(12.5)vs26.1(13.3)mg，P=0.010)。与Ostap组相比，TQL组6~12、12~18、18~24 的吗啡用量明显减少，首次需要吗啡的时间明显延长，内脏疼痛强度评分明显降低。与Ostap阻滞相比，TQL阻滞减少了吗啡用量，并能更好地缓解内脏疼痛，且持续时间更长。中国临床试验注册(CHCTR1800017995)；预结果。
The transmuscular quadratus lumborum (TQL) block and the oblique subcostal transversus abdominis plane (OSTAP) block both contribute to multimodal analgesia after laparoscopic surgery. The objective of this study was to compare the analgesic effects of the TQL block versus OSTAP block after laparoscopic hysterectomy. Prospective single-centre randomised single-blind trial. University-affiliated hospital. Patients aged between 18 and 65 years scheduled for laparoscopic hysterectomy. Patients were randomised into two groups (1:1 ratio) and received bilateral TQL block or bilateral OSTAP block with 0.375% ropivacaine 20 mL on each side before surgery. The primary outcome measure was the cumulative morphine dose in the first 24 hours. The secondary outcome measures were the morphine consumption at each time interval after surgery, the time from the end of surgery to the first need for morphine, the Numerical Rating Scale (NRS) scores for visceral and incisional pain intensity, and the incidence of adverse events. The cumulative morphine dose was significantly lower in the TQL group than in the OSTAP group (17.2 (12.5) vs 26.1 (13.3) mg, p=0.010). Compared with the OSTAP group, the morphine doses from 6 to 12, 12 to 18, and 18 to 24 hours were significantly lower, the time of first need for morphine was significantly longer and the NRS scores for visceral pain intensity were significantly lower in the TQL group. Compared with the OSTAP block, the TQL block reduced morphine consumption and provided better visceral pain relief with a longer duration of effect after laparoscopic hysterectomy. Chinese Clinical Trial Registry (ChiCTR1800017995); pre-results.
登录
查看更多内容
影响因子：
3.6
作者：
Houben, Alan M.;Moreau, Anne-Sophie J.;Joris, Jean L.
通讯作者：
Joris, Jean L.
影响因子：
1.6
作者：
Toker, Melike Korkmaz;Altiparmak, Basak;Demirbilek, Semra Gumus
通讯作者：
Demirbilek, Semra Gumus
DOI：
10.12659/msm.893593
发表时间：
2015-05-07
期刊：
Medical science monitor : international medical journal of experimental and clinical research
影响因子：
--
作者：
Basaran B;Basaran A;Kozanhan B;Kasdogan E;Eryilmaz MA;Ozmen S
通讯作者：
Ozmen S
影响因子：
3.6
作者：
Blanco, Rafael;Ansari, Tarek;Girgis, Emad
通讯作者：
Girgis, Emad
影响因子：
8.8
作者：
Gerbershagen, Hans J.;Aduckathil, Sanjay;Meissner, Winfried
通讯作者：
Meissner, Winfried