Diagnosis of aspergillus keratitis in vivo with confocal microscopy
Diagnosis of aspergillus keratitis in vivo with confocal microscopy
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DOI：
10.1097/00003226-199701000-00006
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发表时间：
1997-01-01
期刊：
影响因子：
2.8
通讯作者：
Sutphin, JE
中科院分区：
文献类型：
--
作者：
Winchester, K;Mathers, WD;Sutphin, JE
共聚焦显微镜提供了一种新的，非侵入性的方式成像的人角膜在体内。其最重要的临床用途之一是感染性角膜炎的诊断和管理。作者使用串联扫描共聚焦显微镜对两例经培养证实的曲霉菌性角膜炎病例的角膜进行成像。真菌菌丝被成像为高对比度的细丝，直径为6 μ m，长度为60至400 μ m。共聚焦显微镜可以是一种快速和安全的诊断工具，以确定是否存在真菌菌丝在人体角膜内。
Confocal microscopy provides a new, noninvasive way of imaging the human cornea in vivo. One of its most important clinical uses is the diagnosis and management of infectious keratitis. The authors used tandem scanning confocal microscopy to image the corneas in two culture-proven cases of Aspergillus keratitis. Fungal hyphae were imaged as high-contrast filaments 6 mu m in diameter from 60 to 400 mu m in length. Confocal microscopy may be a fast and safe diagnostic tool in determining the presence of fungal hyphae in vivo within the human cornea.