Avian B Lymphocyte Subpopulations Origins and Functional Capacities
Avian B Lymphocyte Subpopulations Origins and Functional Capacities
复制标题
禽 B 淋巴细胞亚群的起源和功能
作者：
W. Weber
对鸟类免疫系统发育和功能的研究在很大程度上是对T和B淋巴细胞功能二分法的初步认识(Glick等人。1956年，库珀等人提出。1966a)。从随后对几个物种的研究中，越来越明显的是，这些主要的淋巴细胞类别中的每一个都由物理和功能上不同的亚群组成。具体参考B细胞群体，表膜标记物的检测包括Ig(Raff1970，Kincade等人。1971年，Rabellino&Grey 1971)，Fc受体(Basten等人1972)，钙受体(Bianco等人)。1970)和小鼠特异性B淋巴细胞抗原(MBLA)(Ra2等人)。1971年)导致了对B细胞的进一步表征。这些受体中的一些仅存在于部分B细胞上(Dukor等a)。1971年)是B细胞亚群可能存在的一个迹象。进一步的观察表明亚群的存在包括未激发的和抗原激发的B淋巴细胞的迁移模式、组织分布和周转率的差异(Strober&Dilley 1973)，B细胞的归巢模式。
Studies on the development and function of the avian immune system were largely responsible for the initial recognition of the functional dichotomy of T and B lymphocytes (Glick et al. 1956, Cooper et al. 1966a). From subsequent studies in several species it has become increasingly evident that each of these major lymphocyte classes consists of physically and functionally different subpopulations. With specific reference to the B cell population, the detection of surface membrane markers including Ig (Raff 1970, Kincade et al. 1971, Rabellino & Grey 1971), Fc receptors (Basten et al. 1972), Ca receptors (Bianco et al. 1970) and a mouse specific B lymphocyte antigen (MBLA) (Ra2 et al. 1971) has led to further characterization of B cells. The presence of some of these receptors on only a proportion of B cells (Dukor et a]. 1971) is one indication for the possible existence of B cell subpopulations. Additional observations suggesting the existence of subpopulations include differences in migration pattern, tissue distribution and turnover rate of unprimed and antigen primed B lymphocytes (Strober & Dilley 1973), homing patterns of B cells ia Iym-
诱导 T 细胞分化。
DOI：
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发表时间：
1984
期刊：
Zhonghua Minguo wei sheng wu ji mian yi xue za zhi = Chinese journal of microbiology and immunology
影响因子：
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作者：
Shen,FW
通讯作者：
Shen,FW