Assessment of the quality of life of patients with major depression.
Assessment of the quality of life of patients with major depression.
复制标题
重度抑郁症患者的生活质量评估。
DOI：
10.1176/ps.48.2.224
复制
发表时间：
1997
期刊：
影响因子：
--
通讯作者：
Grant,I
中科院分区：
文献类型：
--
作者：
Pyne,JM;Patterson,TL;Kaplan,RM;Gillin,JC;Koch,WL;Grant,I
目的本研究探讨了重度抑郁症患者的生活质量测量与抑郁症状测量之间的关系。方法使用多种测量方法对来自圣地亚哥退伍军人事务医疗中心及周边地区的 100 名原发性重度抑郁症患者和 61 名对照受试者进行比较，包括幸福质量 (QWB) 量表、汉密尔顿抑郁量表和贝克抑郁量表。结果分析后控制了年龄、性别、精神疾病家族史和共病轴 III诊断后，受试者的 QWB 得分与汉密尔顿量表和贝克量表得分显着相关。抑郁症状的严重程度与 QWB 测量的生活质量呈负相关，与控制的变量无关。结论 QWB 对诊断为重度抑郁症的患者的抑郁症状敏感。与抑郁症精神症状相关的生活质量下降与在身体疾病患者中观察到的情况相当。
ObjectiveThis study examined the relationship between a measure of quality of life and measures of depressive symptoms among patients with major depression.MethodsOne hundred patients with primary major depression and 61 control subjects from the San Diego Veterans Affairs Medical Center and surrounding area were compared using a variety of measures, including the Quality of Well-Being (QWB) scale, the Hamilton Rating Scale for Depression, and the Beck Depression Inventory.ResultsAfter analyses controlled for age, gender, family history of mental illness, and comorbid axis III diagnosis, subjects' scores on the QWB were significantly correlated with their scores on the Hamilton scale and Beck inventory. The severity of depressive symptoms was inversely related to quality of life as measured by the QWB, independent of the variables that were controlled for.ConclusionsThe QWB is sensitive to symptoms of depression among patients diagnosed with major depression. The reduction in quality of life associated with psychiatric symptoms of depression is comparable to that observed among physically ill patients.