ROLE OF ACETYLCHOLINE-RECEPTOR SUBUNITS IN GATING OF THE CHANNEL
ROLE OF ACETYLCHOLINE-RECEPTOR SUBUNITS IN GATING OF THE CHANNEL
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DOI：
10.1038/318538a0
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发表时间：
1985-01-01
期刊：
影响因子：
64.8
通讯作者：
NUMA, S
中科院分区：
文献类型：
--
作者：
SAKMANN, B;METHFESSEL, C;NUMA, S
用克隆的互补DNA在非洲爪蟾卵母细胞中制备了电鳐和小牛乙酰胆碱受体及其亚基的杂交体。单通道电流测量表明，这些受体形成的通道具有相似的电导，但具有不同的门控行为。
The Torpedo and calf acetylcholine receptors and hybrids composed of subunits from the two species have been produced in Xenopus oocytes by the use of the cloned complementary DNAs. Single-channel current measurements indicate that these receptors form channels of similar conductance but with different gating behavior.