Gradient generation platforms: new directions for an established microfluidic technology.
Gradient generation platforms: new directions for an established microfluidic technology.
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梯度生成平台:已建立微流体技术的新方向。
DOI:
10.1039/c4lc00448e
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发表时间:
2014-09-07
期刊:
影响因子:
6.1
通讯作者:
Beebe DJ
中科院分区:
文献类型:
--
作者:
Berthier E;Beebe DJ
Microscale platforms are enabling for cell-based studies as they allow the recapitulation of physiological conditions such as extracellular matrix (ECM) configurations and soluble factors interactions. Gradient generation platforms have been one of the few applications of microfluidics that have begun to be translated to biological laboratories and may become a new “gold standard”. Though gradient generation platforms are now established, their full potential has not yet been realized. Here, we will provide our perspective on milestones achieved in the development of gradient generation and cell migration platforms, as well as emerging directions such as using cell migration as a diagnostic readout and attaining mechanistic information from cell migration models.
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影响因子:
2.5
作者:
Ambravaneswaran, Vijayakrishnan;Wong, Ian Y.;Irimia, Daniel
通讯作者:
Irimia, Daniel
DOI:
10.1039/c4ib00015c
发表时间:
2014-05
期刊:
Integrative biology : quantitative biosciences from nano to macro
影响因子:
--
作者:
Cavnar SP;Ray P;Moudgil P;Chang SL;Luker KE;Linderman JJ;Takayama S;Luker GD
通讯作者:
Luker GD
影响因子:
2.5
作者:
Bischel, Lauren L.;Casavant, Benjamin P.;Beebe, David J.
通讯作者:
Beebe, David J.
影响因子:
3.2
作者:
Cate, David M.;Sip, Christopher G.;Folch, Albert
通讯作者:
Folch, Albert
DOI:
10.1083/jcb.200810041
发表时间:
2009-02-23
期刊:
The Journal of cell biology
影响因子:
--
作者:
Doyle AD;Wang FW;Matsumoto K;Yamada KM
通讯作者:
Yamada KM