CD10 positive thyroid marginal zone non-Hodgkin lymphoma.
CD10 positive thyroid marginal zone non-Hodgkin lymphoma.
复制标题
CD10 阳性甲状腺边缘区非霍奇金淋巴瘤。
DOI：
--
复制
发表时间：
1999
影响因子：
3.4
通讯作者：
S. Braye
中科院分区：
文献类型：
--
作者：
E. Millar;S. Waldron;A. Spencer;S. Braye
一位72岁的女性，她的甲状腺右叶肿胀。细针穿刺和流式细胞术显示表达CD 10的B细胞克隆群，诊断为滤泡中心细胞淋巴瘤。随后切除甲状腺显示边缘区非霍奇金淋巴瘤的典型组织学特征。聚合酶链反应显示无t（14;18）证据。免疫组化证实CD 10阳性和LN 1（CD w75）表达。这是第二个边缘区淋巴瘤异常表达CD 10的报道.
A 72 year old woman presented with swelling of the right lobe of her thyroid gland. Fine needle aspiration and flow cytometry showed a clonal population of B cells expressing CD10 and a diagnosis of follicle centre cell lymphoma was made. Subsequent excision of the thyroid showed the typical histological features of a marginal zone non-Hodgkin lymphoma. Polymerase chain reaction showed no evidence of t (14;18). Immunohistochemistry confirmed CD10 positivity and LN1 (CDw75) expression. This is only the second report of aberrant expression of CD 10 by a marginal zone lymphoma.