Carbapenem-Resistant Pseudomonas aeruginosa Bacteremia: Risk Factors for Mortality and Microbiologic Treatment Failure
Carbapenem-Resistant Pseudomonas aeruginosa Bacteremia: Risk Factors for Mortality and Microbiologic Treatment Failure
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DOI：
10.1128/aac.01243-16
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发表时间：
2017-01-01
影响因子：
4.9
通讯作者：
Nguyen, M. Hong
中科院分区：
文献类型：
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作者：
Buehrle, Deanna J.;Shields, Ryan K.;Nguyen, M. Hong
We reviewed 37 patients treated for bacteremia due to carbapenemresistant (CR) Pseudomonas aeruginosa. Although 65% of isolates were multiple-drug resistant, therapeutic options were available, as all were susceptible to >= 1 antibiotic. A total of 92% of patients received active antimicrobial therapy, but only 57% received early active therapy (within 48 h). Fourteen-day mortality was 19%. Microbiologic failure occurred in 29%. The Pitt bacteremia score (P = 0.046) and delayed active therapy (P = 0.027) were predictive of death and microbiologic failure, respectively.
