The interactions of alpha 2HS glycoprotein with metalloproteinases.
The interactions of alpha 2HS glycoprotein with metalloproteinases.
复制标题
α2HS 糖蛋白与金属蛋白酶的相互作用。
DOI：
10.1080/15216549600201482
复制
发表时间：
1996
期刊：
影响因子：
--
通讯作者：
Green,B
中科院分区：
文献类型：
--
作者：
Ochieng,J;Green,B
The objective of the present analyses was to determine whether matrix metalloproteinases interact with alpha 2HS glycoprotein, the human homologue of bovine fetuin. Alpha 2HS glycoprotein was incubated with metalloproteinases at 1:1 and 1:10 molar ratios. The serum glycoprotein was completely degraded by gelatinase‐A and matrilysin at the higher enzyme concentration after an overnight incubation at 37°C. The data show that gelatinase‐A, matrilysin and gelatinase‐B do interact with alpha 2HS glycoprotein and that gelatinase‐B associates most tightly with the serum glycoprotein.
