Prolonged suppression of cough after inhalation of lidocaine in a patient with sarcoid.
Prolonged suppression of cough after inhalation of lidocaine in a patient with sarcoid.
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结节病患者吸入利多卡因后长期抑制咳嗽。
DOI：
10.1001/jama.1984.03350170058022
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发表时间：
1984
期刊：
影响因子：
--
通讯作者：
M. B. Kirkpatrick
中科院分区：
文献类型：
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作者：
R. V. Sanders;M. B. Kirkpatrick
慢性持续性咳嗽可引起诊断和治疗上的困难。最近的研究主要针对慢性咳嗽的诊断评估，这些研究表明，对病因进行充分治疗可有效抑制咳嗽。1，2然而，在某些患者中，慢性咳嗽可能是由对治疗无反应的肺部疾病引起的。事实上，慢性咳嗽可能比任何其他肺部症状（如呼吸困难）更具致残性，因此抑制咳嗽成为主要的治疗目标。我们描述了一个病人与结节病致残咳嗽谁有一个不足的反应可待因，但谁有长期抑制他的咳嗽吸入利多卡因雾化后。病例报告一位34岁男性于1976年经胸部X线片及临床诊断为肺结节病，1978年经纵隔淋巴结活检证实为非干酪化肉芽肿。他服用了强的松
CHRONIC persistent cough can present both difficult diagnostic and therapeutic problems. Recent studies have primarily addressed the diagnostic evaluation of chronic cough, and these studies suggest that adequate treatment of the cause is highly effective in suppressing the cough.1,2In some patients, however, chronic cough may be caused by pulmonary disease that is unresponsive to therapy. Indeed, chronic cough may be more disabling than any other pulmonary symptom, such as dyspnea, and suppression of the cough then becomes a major therapeutic goal. We describe a patient with sarcoid with disabling cough who had an inadequate response to codeine, but who has had prolonged suppression of his cough after inhalation of nebulized lidocaine. Report of a Case A 34-year-old man was diagnosed as having pulmonary sarcoid in 1976 by chest roentgenogram and clinical course, confirmed in 1978 by mediastinal lymph node biopsy specimen showing noncaseating granulomata. He has taken prednisone