Database for mobile group II introns
Database for mobile group II introns
复制标题
DOI：
10.1093/nar/gkg049
复制
发表时间：
2003-01-01
影响因子：
14.9
通讯作者：
Zimmerly, S
中科院分区：
文献类型：
--
作者：
Dai, LX;Toor, N;Zimmerly, S
第二类内含子是细菌和低等真核细胞器中发现的自剪接RNA和逆转录元件。在过去的几年里，由于基因组测序计划，它们在细菌中被发现了惊人的数量；然而，大多数新测序的内含子都没有被正确识别。为了提供有关内含子的正确信息，特别是细菌中的内含子，我们已经启动了一个正在进行的第二类移动内含子的网站数据库。网站上的信息包括：(1)关于第二组内含子的介绍性信息；(2)关于内含子RNA结构和内含子编码蛋白质亚家族的详细信息；(3)具有正确边界、RNA二级结构和其他详细信息的已识别内含子清单；以及(4)系统发育和进化信息。比较数据应有助于研究第二类内含子的功能、传播和进化。该数据库可通过http：//www.访问。Fp。加州大学卡尔加里分校Ca/group2内含子/。
Group II introns are self-splicing RNAs and retroelements found in bacteria and lower eukaryotic organelles. During the past several years, they have been uncovered in surprising numbers in bacteria due to the genome sequencing projects; however, most of the newly sequenced introns are not correctly identified. We have initiated an ongoing web site database for mobile group II introns in order to provide correct information on the introns, particularly in bacteria. Information in the web site includes: ( 1) introductory information on group II introns; ( 2) detailed information on subfamilies of intron RNA structures and intron-encoded proteins; (3) a listing of identified introns with correct boundaries, RNA secondary structures and other detailed information; and ( 4) phylogenetic and evolutionary information. The comparative data should facilitate study of the function, spread and evolution of group II introns. The database can be accessed at http: / / www. fp. ucalgary. ca/ group2introns/.