ARE THERE SEROTONERGIC PROJECTIONS FROM RAPHE AND RETROTRAPEZOID NUCLEI TO THE VENTRAL RESPIRATORY GROUP IN THE RAT
ARE THERE SEROTONERGIC PROJECTIONS FROM RAPHE AND RETROTRAPEZOID NUCLEI TO THE VENTRAL RESPIRATORY GROUP IN THE RAT
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DOI：
10.1016/0304-3940(89)90007-4
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发表时间：
1989-10-23
影响因子：
2.5
通讯作者：
FELDMAN, JL
中科院分区：
文献类型：
--
作者：
CONNELLY, CA;ELLENBERGER, HH;FELDMAN, JL
用免疫组织化学和逆行标记技术研究了大鼠中缝和延髓腹外侧区的肾上腺素能神经元与向吻侧腹侧呼吸群投射的神经元的关系。5-羟色胺能和非5-羟色胺能神经元逆行标记的罗丹明珠被发现混杂在更大的人口中，中缝苍白，暗和大的5-羟色胺免疫反应阳性神经元。此外，在大鼠延髓腹外侧区发现了一个类似于猫小斜方后核的细胞群。后梯形神经元，其中只表现出同侧的预测腹侧呼吸组，位于侧面的簇腹侧表面附近的神经元能细胞，但没有5-羟色胺免疫反应。
The relationship of serotonergic neurons in raphe and ventrolateral medullary regions to neurons projecting to the rostral ventral respiratory group in the rat investigated using combined immunohistochemical and retrograde labeling techniques. Serotonergic and non-serotonergic neurons retrogradely labeled with rhodamine beads were found intermingled in the larger population of serotonin-immunoreactive neurons in raphe pallidus, obscurus and magnus. In addition, a cell group analogous to the retrotrapezoid nucleus in the cat was identified in the rat ventrolateral medulla. Retrotrapezoid neurons, which exhibited exclusively ipsilateral projections to the ventral respiratory group, were located lateral to clusters of serotonergic cells near the ventral surface, but were not serotonin immunoreactive.