Inhibitory control in mind and brain 2.0: blocked-input models of saccadic countermanding.
Inhibitory control in mind and brain 2.0: blocked-input models of saccadic countermanding.
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DOI：
10.1037/a0038893
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发表时间：
2015-04
影响因子：
5.4
通讯作者：
Palmeri TJ
中科院分区：
文献类型：
--
作者：
Logan GD;Yamaguchi M;Schall JD;Palmeri TJ
扫视撤销的交互式竞赛模型假设反应抑制是由与注视转移神经元识别的go单元和与注视保持神经元识别的stop单元之间的交互引起的，其中stop单元的激活抑制go单元中的激活的增长以防止其达到阈值。交互式竞赛模型解释了猴子执行停止信号任务的行为数据和预测生理数据。我们提出了一个替代模型，假设反应抑制的结果，从阻止输入到围棋单位。我们表明，阻塞输入模型占行为数据准确的原始交互式比赛模型和预测方面的生理数据更准确。我们扩展了模型，以解决稳态固定期之前，去刺激，并发现阻塞输入模型比交互式比赛模型更适合。我们考虑一个模型，其中固定活动时，停止信号发生，并发现它适合以及阻塞输入模型，但预测非常高的稳态固定活动后，响应被抑制。我们讨论了连接计算模型到神经机制的替代连接命题，从模型模仿中吸取的教训，以及从撤销扫视到撤销其他类型反应的概括。
The interactive race model of saccadic countermanding assumes that response inhibition results from an interaction between a go unit, identified with gaze-shifting neurons, and a stop unit, identified with gaze-holding neurons, in which activation of the stop unit inhibits the growth of activation in the go unit to prevent it from reaching threshold. The interactive race model accounts for behavioral data and predicts physiological data in monkeys performing the stop-signal task. We propose an alternative model that assumes that response inhibition results from blocking the input to the go unit. We show that the blocked-input model accounts for behavioral data as accurately as the original interactive race model and predicts aspects of the physiological data more accurately. We extend the models to address the steady-state fixation period before the go stimulus is presented and find that the blocked-input model fits better than the interactive race model. We consider a model in which fixation activity is boosted when a stop signal occurs and find that it fits as well as the blocked input model but predicts very high steady-state fixation activity after the response is inhibited. We discuss the alternative linking propositions that connect computational models to neural mechanisms, the lessons to be learned from model mimicry, and generalization from countermanding saccades to countermanding other kinds of responses.