MYOSIN - A LINK BETWEEN STREPTOCOCCI AND HEART
MYOSIN - A LINK BETWEEN STREPTOCOCCI AND HEART
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DOI：
10.1126/science.2578225
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发表时间：
1985-01-01
期刊：
影响因子：
56.9
通讯作者：
CUNNINGHAM, MW
中科院分区：
文献类型：
--
作者：
KRISHER, K;CUNNINGHAM, MW
鼠抗化脓性链球菌单克隆抗体与骨骼肌肌球蛋白反应。人心脏组织提取物中的高分子量蛋白质与抗S.化脓性链球菌也与心室肌球蛋白的单克隆抗体反应。用S.化脓性链球菌同时去除了对S.化脓性或肌球蛋白。肌球蛋白显然与S.化脓
Murine monoclonal antibodies to Streptococcus pyogenes reacted with skeletal muscle myosin. High MW proteins in extracts of human heart tissue that reacted with an antibody to S. pyogenes also reacted with a monoclonal antibody to ventricular myosin. Adsorption of the antibody to streptococci with S. pyogenes simultaneously removed reactivity of the antibody for S. pyogenes or myosin. Myosin apparently shares immunodeterminants with a component of S. pyogenes.