Making inferences about projected completors in longitudinal studies.
Making inferences about projected completors in longitudinal studies.
复制标题
在纵向研究中对预计完成者进行推断。
DOI:
10.1081/bip-200035467
复制
发表时间:
2004
影响因子:
1.1
通讯作者:
Helms,RonaldW
中科院分区:
文献类型:
--
作者:
Bowman,FDuBois;Stewart,PaulW;Sen,PranabK;Helms,RonaldW
In this article, we present methodology for making inferences about projected completors in the presence of attrition. The approach is motivated by a clinical trial that investigates a treatment for disability among individuals who sustain severe head injuries. Although most studies attempt to make inferences about the entire study population, our application poses important scientific questions targeting individuals who are likely to complete the study or to remain on protocol for a specified time period. We propose using measures of each individual's dropout inclination to identify projected completors and then building a stratified response model based on projected completion status. We present several prediction measures along with procedures for evaluating accuracy with respect to observed dropout. Estimation of model parameters proceeds using maximum likelihood and restricted maximum likelihood methods. We illustrate the utility of our proposed analysis by using the motivating disability data example.