Distinct sensorimotor feedback loops for dynamic and static control of primate precision grip
Distinct sensorimotor feedback loops for dynamic and static control of primate precision grip
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DOI：
10.1038/s42003-020-0861-0
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发表时间：
2019-05
影响因子：
5.9
通讯作者：
T. Oya;Tomohiko Takei;K. Seki
中科院分区：
文献类型：
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作者：
T. Oya;Tomohiko Takei;K. Seki
意志性肢体运动控制包括动态和静态肌肉动作。这种不同的行为是如何通过分离或共享的神经回路来控制的，目前仍难以捉摸。在这篇文章中，我们通过研究猕猴在精确握握时脊髓局部场电位(LFP)和前肢肌电活动(EMG)以及运动皮质LFP和EMG之间的神经元一致性，来探索灵长类手部动作中动态和静态控制的潜在分离。我们观察到在分离的阶段，脊髓和运动皮质的肌电出现β-范围一致性；握力阶段出现脊髓一致性，而握持阶段出现皮质一致性。此外，两种相干性都受到双向相互作用的影响，具有合理的潜伏期，如β振荡周期。这些结果表明，包括脊髓和皮质结构的专用反馈电路是灵巧手动作的动态和静态控制的基础。
Volitional limb motor control involves dynamic and static muscle actions. It remains elusive how such distinct actions are controlled through separated or shared neural circuits. Here we explored the potential separation for dynamic and static controls in primate hand actions, by investigating the neuronal coherence between local field potentials (LFPs) of the spinal cord and the forelimb electromyographic activity (EMGs), and LFPs of the motor cortex and the EMGs during the performance of a precision grip in macaque monkeys. We observed the emergence of beta-range coherence with EMGs at spinal cord and motor cortex in the separated phases; spinal coherence during the grip phase and cortical coherence during the hold phase. Further, both of the coherences were influenced by bidirectional interactions with reasonable latencies as beta oscillatory cycles. These results indicate that dedicated feedback circuits comprising spinal and cortical structures underlie dynamic and static controls of dexterous hand actions.