Overview of SARS-CoV-2 infection in adults living with HIV.
Overview of SARS-CoV-2 infection in adults living with HIV.
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DOI：
10.1016/s2352-3018(21)00070-9
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发表时间：
2021-05
期刊：
影响因子：
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通讯作者：
COVID-19 in HIV Investigators
中科院分区：
文献类型：
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作者：
Ambrosioni J;Blanco JL;Reyes-Urueña JM;Davies MA;Sued O;Marcos MA;Martínez E;Bertagnolio S;Alcamí J;Miro JM;COVID-19 in HIV Investigators
全球已报告约250万人死亡，超过1.1亿例COVID-19病例。虽然最初艾滋病毒感染似乎不是COVID-19或更严重疾病的风险因素，但最近的大型研究表明，艾滋病毒感染者（特别是CD4细胞计数低或未经治疗的艾滋病毒感染者）的临床病程可能比艾滋病毒阴性者更严重。此外，2019冠状病毒病大流行扰乱了全球艾滋病毒预防和治疗服务，给基本活动的连续性带来巨大挑战。我们回顾了COVID-19在艾滋病毒感染者中最相关的特征，并强调了需要进一步研究的主题。
Around 2·5 million deaths and more than 110 million COVID-19 cases have been reported globally. Although it initially appeared that HIV infection was not a risk factor for COVID-19 or more severe disease, more recent large studies suggest that people living with HIV (particularly with low CD4 cell counts or untreated HIV infection) might have a more severe clinical course than those who are HIV-negative. Moreover, the COVID-19 pandemic has disrupted HIV prevention and treatment services worldwide, creating huge challenges to the continuity of essential activities. We have reviewed the most relevant features of COVID-19 in people living with HIV and highlighted topics where further research is required.