Preventive effects of preoperative ramelteon on postoperative delirium in Asian elderly population: A randomized, double-blind, placebo-controlled trial, and a systematic review and meta-analysis
Preventive effects of preoperative ramelteon on postoperative delirium in Asian elderly population: A randomized, double-blind, placebo-controlled trial, and a systematic review and meta-analysis
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术前雷美替胺对亚洲老年人群术后谵妄的预防作用：一项随机、双盲、安慰剂对照试验以及系统评价和荟萃分析
DOI：
10.1016/j.ajp.2022.103282
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发表时间：
2022
影响因子：
9.5
通讯作者：
Hishimoto Akitoyo
中科院分区：
文献类型：
--
作者：
Tanifuji Takaki;Otsuka Ikuo;Okazaki Satoshi;Horai Tadasu;So Ryuhei;Shiroiwa Kyoichi;Mouri Kentaro;Tanaka Motofumi;Ohmoto Nobuko;Sora Ichiro;Hirai Midori;Fukumoto Takumi;Ku Yonson;Hishimoto Akitoyo
我们进行了随机对照试验，以检验小剂量拉梅尔酮是否能减少术后精神错乱。我们对随机对照试验进行了亚洲随机对照试验的荟萃分析，以了解雷米尔顿对术后精神错乱的影响。荟萃分析显示，雷美尔顿减少了亚洲老年人的术后精神错乱。
HighlightsRCT was performed to test whether low-dose ramelteon reduces postoperative delirium.We ran Asian meta-analysis of RCTs for ramelteon effects on postoperative delirium.The meta-analysis showed ramelteon reduced postoperative delirium in Asian elderly.