Antiviral activity of Achyrocline flaccida Wein DC aqueous extract
Antiviral activity of Achyrocline flaccida Wein DC aqueous extract
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Achyrocline flaccida Wein DC 水提取物的抗病毒活性
DOI：
10.1002/ptr.2650090404
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发表时间：
1995
影响因子：
7.2
通讯作者：
R. Campos
中科院分区：
文献类型：
--
作者：
G. García;L. Cavallaro;A. Broussalis;G. Ferraro;V. Martino;R. Torres;J. Coussio;R. Campos
糜烂水提取物 (AE) 在体外对疱疹病毒家族的不同成员（单纯疱疹病毒 1 型和 2 型、人巨细胞病毒、牛疱疹病毒）表现出真正的抗病毒活性，对伪狂犬病病毒的活性较低。该提取物对某些 RNA（裸露的和有包膜的）病毒和腺病毒没有活性。该提取物没有杀病毒作用，但其抗病毒指数（AI）足够高，足以证明进一步分析的合理性。初步表征表明病毒复制的早期步骤受到水提取物的影响。
Aqueous extracts (AE) of chyrocline flaccida exhibit true antiviral activity in vitro against different members of the Herpesvirus family (herpes simplex virus type 1 and 2, human cytomegalovirus, bovine herpesvirus and lower activity with pseudorabies virus). The extract had no activity against some RNA (naked and enveloped) viruses and adenoviruses. The extract was not virucidal but its antiviral index (AI) was sufficiently high to justify further analysis. A preliminary characterization indicates that an early step of viral replication was affected by the aqueous extract.