Effect of carbogen (95% O2/5% CO2) on retinal oxygenation in dark-adapted anesthetized cats.
Effect of carbogen (95% O2/5% CO2) on retinal oxygenation in dark-adapted anesthetized cats.
复制标题
效果%20of%20carbogen%20(95%%20O2/5%%20CO2)%20on%20视网膜%20氧合%20in%20暗适应%20麻醉%20只猫。
DOI：
10.1080/02713680701459250
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发表时间：
2007
影响因子：
2
通讯作者：
Linsenmeier,RobertA
中科院分区：
文献类型：
--
作者：
Chung,ChristinaK;Linsenmeier,RobertA
This work assessed the relative effects of inspiring carbogen (95% O2/5% CO2) and 100% O2on intraretinal PO2and oxygen consumption in the cat retina. Oxygen microelectrodes were used to measure the distribution of oxygen in the central retina of dark-adapted anesthetized cats during normoxia, 100% O2 breathing, and carbogen breathing. Profiles of oxygen tension (PO2) as a function of retinal depth were recorded. Changes in PO2caused by the transient administration of carbogen and 100% oxygen were also measured at selected retinal depths. Average PO2values at the choroid, at the boundary between the inner and outer retina, and across the inner retina were significantly higher during inspiration of carbogen than 100% O2. There were no significant differences among conditions in outer retinal oxygen consumption. During the transient gas administration, average changes in PO2generally increased with depth. At the end of gas administration, the decay of PO2within the retina occurred quickly, meaning that short-term gas administration may have little therapeutic value.
