`Black Spots' and Hyaline Pleural Plaques on the Parietal Pleura of 150 Urban Necropsy Cases
`Black Spots' and Hyaline Pleural Plaques on the Parietal Pleura of 150 Urban Necropsy Cases
复制标题
150例城市尸检壁层胸膜“黑点”及透明胸膜斑块
DOI：
10.1097/00000478-200209000-00010
复制
发表时间：
2002
期刊：
影响因子：
--
通讯作者：
P. de Vuyst
中科院分区：
文献类型：
--
作者：
K. Mitchev;P. Dumortier;P. de Vuyst
肺与壁层胸膜之间缺乏任何直接联系，这引发了人们对胸膜迁移和吸入颗粒滞留机制的质疑。有人建议，壁胸膜的特定区域吸收和保留胸膜空间的无机颗粒，包括碳色素和石棉纤维，并可能是由矿物纤维引起的病理变化的起点。这些收集粒子的结构被称为“黑点”。为了研究它们的分布、宏观外观以及与胸膜斑的可能关系，我们检查了150例连续尸检的城市居民（平均年龄67.7 ± 12.9岁）的壁层胸膜。对斑点的大小和强度进行评分，并与胸膜斑存在的信息一起记录在计算机方案上。在92.7%的病例中观察到黑点。它们主要位于下肋带和胸膜带，与参与胸膜腔清除的结构的解剖分布相对应。得分与性别和年龄相关。黑色斑点的主要位置与透明胸膜斑之间没有关系。
The absence of any direct connection between the lung and the parietal pleura raises questions about the mechanisms of pleural migration and retention of inhaled particles. It has been suggested that specific areas of parietal pleura absorb and retain inorganic particles from the pleural space, including carbon pigments and asbestos fibers, and could be starting points for pathologic changes induced by mineral fibers. These particle-collecting structures have been called “black spots.” To study their distribution, macroscopic appearance, and possible relationship with pleural plaques, the parietal pleura of 150 consecutive necropsies of urban dwellers (mean age 67.7 ± 12.9 years) were examined. The size and intensity of spots were scored and recorded on a computer scheme together with information of the presence of pleural plaques. Black spots were observed in 92.7% of the cases. They were mainly located in the lower costal and diaphragmatic zones and could correspond to the anatomic distribution of structures involved in pleural cavity clearance. Scores correlated with sex and age. There was no relationship between the predominant locations of black spots and hyaline pleural plaques.