Biomagnetic characterization of spatiotemporal parameters of the gastric slow wave
Biomagnetic characterization of spatiotemporal parameters of the gastric slow wave
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DOI：
10.1111/j.1365-2982.2006.00794.x
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发表时间：
2006-08-01
影响因子：
3.5
通讯作者：
Richards, W. O.
中科院分区：
文献类型：
--
作者：
Bradshaw, L. A.;Irimia, A.;Richards, W. O.
某些胃部疾病影响胃慢波的时空参数。而胃电图（EGG）评价电位，以确定主要的时间参数，基本的物理限制所施加的体积传导性能的腹部建议胃磁场的评价。本文用多通道超导量子干涉仪对20名正常人进行了餐前、餐后胃磁图（MGG）的研究。计算胃电慢波的频率和振幅参数。我们确定了正常的胃慢波活动，餐前频率为2.6 +/- 0.5 cpm，餐后为2.8 +/- 0.3 cpm。除了频率和振幅之外，应用于多通道MGG的表面电流密度映射的使用使我们能够可视化传播慢波并计算其传播速度（餐前6.6 +/- 1.0 mm s（-1）和餐后7.4 +/- 0.4 mm s（-1））。而MGG和EGG信号表现出很强的相关性，MGG和测压之间的相关性很小。胃电图不仅记录了胃慢波的频率动力学，而且还表征了胃的传播。MGG主要反映胃电活动，但不是其机械活动。
Certain gastric disorders affect spatiotemporal parameters of the gastric slow wave. Whereas the electrogastrogram (EGG) evaluates electric potentials to determine primarily temporal parameters, fundamental physical limitations imposed by the volume conduction properties of the abdomen suggest the evaluation of gastric magnetic fields. We used a multichannel superconducting quantum interference device magnetometer to study the magnetogastrogram (MGG) in 20 normal human subjects before and after a test meal. We computed the frequency and amplitude parameters of the gastric slow wave from MGG. We identified normal gastric slow wave activity with a frequency of 2.6 +/- 0.5 cycles per minute (cpm) preprandial and 2.8 +/- 0.3 cpm postprandial. In addition to frequency and amplitude, the use of surface current density mapping applied to the multichannel MGG allowed us to visualize the propagating slow wave and compute its propagation velocity (6.6 +/- 1.0 mm s(-1) preprandial and 7.4 +/- 0.4 mm s(-1) postprandial). Whereas MGG and EGG signals exhibited strong correlation, there was very little correlation between the MGG and manometry. The MGG not only records frequency dynamics of the gastric slow wave, but also characterizes gastric propagation. The MGG primarily reflects the underlying gastric electrical activity, but not its mechanical activity.