Prevalence of diabetic retinopathy in adult Latinos
Prevalence of diabetic retinopathy in adult Latinos
复制标题
DOI：
10.1016/j.ophtha.2004.03.002
复制
发表时间：
2004-07-01
期刊：
影响因子：
13.7
通讯作者：
Azen, SP
中科院分区：
文献类型：
--
作者：
Varma, R;Torres, M;Azen, SP
目的：估计糖尿病视网膜病变（DR）的年龄和性别特异性患病率，并确定糖尿病的类型、病程和治疗与成年拉丁美洲人DR患病率的相关性。设计：基于人群的横断面研究。参与者：来自加州洛杉矶6个人口普查区的6357名40岁及以上的拉丁美洲人。方法：研究队列包括所有自认为主要为墨西哥血统的40岁及以上的拉丁美洲人，居住在加州洛杉矶县拉蓬特的6个人口普查区。所有诊断为糖尿病的参与者都接受了完整的眼科检查，包括立体眼底照相（7个标准的早期治疗糖尿病视网膜病变研究领域）。照片进行了分级，在一个掩蔽的方式使用修改后的Airlie House分级系统，以评估存在和严重程度的DR。主要结果措施：非增殖性DR，增殖性DR，黄斑水肿的患病率。结果：1263名参与者明确糖尿病，分级眼底照片可在1217名参与者（96%）。在这1217名参与者中，46.9%患有DR。严重的非增殖性DR和增殖性DR分别出现在4.4%和6.1%的糖尿病患者中。在所有糖尿病患者中，10.4%观察到黄斑水肿，6.2%观察到具有临床意义的黄斑水肿。不存在年龄或性别相关差异。调整糖尿病的持续时间后，DR的患病率是相似的人与1型和2型diabetes.Conclusions：我们的数据表明，DR的患病率是很高的主要墨西哥血统的拉丁美洲人。随着糖尿病病程的延长，DR患病率的增加强调了拉丁美洲人早期诊断和管理的公共卫生重要性。需要进一步的发病率和进展的数据，以更好地了解DR在拉丁美洲人的自然史。(C)2004年，美国眼科学会。
Objective: To estimate age- and gender-specific prevalence of diabetic retinopathy (DR) and to determine the association of type, duration, and treatment of diabetes with the prevalence of DR in adult Latinos.Design: Population-based cross-sectional study.Participants: Six thousand three hundred fifty-seven Latinos aged 40 years and older from 6 census tracts in Los Angeles, California.Methods: The study cohort consisted of all self-identified Latinos of primarily Mexican ancestry aged 40 years and older residing in 6 census tracts in La Puente, Los Angeles County, California. All participants diagnosed with diabetes underwent a complete ophthalmologic examination, including stereoscopic fundus photography (7 standard Early Treatment Diabetic Retinopathy Study fields). Photographs were graded in a masked manner using a modified Airlie House Grading System to assess presence and severity of DR.Main Outcome Measures: Prevalence of nonproliferative DR, proliferative DR, and macular edema.Results: Of 1263 participants with definite diabetes mellitus, gradable fundus photographs were available in 1217 participants (96%). Of those 1217 participants, 46.9% had DR. Severe nonproliferative DR and proliferative DR were present in 4.4% and 6.1% of diabetics, respectively. Macular edema was observed in 10.4% and clinically significant macular edema was observed in 6.2% of all diabetics. No age- or gender-related differences were present. After adjusting for duration of diabetes, the prevalence of DR was similar in persons with type 1 and type 2 diabetes.Conclusions: Our data suggest that the prevalence of DR is high among Latinos of primarily Mexican ancestry. The increase in prevalence of DR with longer duration of diabetes emphasizes the public health importance of early diagnosis and management in Latinos. Further data on incidence and progression are required to understand better the natural history of DR in Latinos. (C) 2004 by the American Academy of Ophthalmology.