Biomimic preparation of highly dispersible silica nanoparticles based polymer nanocomposites
Biomimic preparation of highly dispersible silica nanoparticles based polymer nanocomposites
复制标题
高分散二氧化硅纳米粒子基聚合物纳米复合材料的仿生制备
DOI：
10.1016/j.ceramint.2015.08.072
复制
发表时间：
2015-12-01
影响因子：
5.2
通讯作者：
Wei, Yen
中科院分区：
文献类型：
--
作者：
Heng, Chunning;Liu, Meiying;Wei, Yen
二氧化硅纳米粒子（SiO2 NPs）具有无臭、无污染、光学透明、化学惰性和良好的生物相容性等优点，在许多领域得到了广泛的应用。然而，为了实现更好的性能，通常需要对SiO2 NPs进行表面改性以增强它们的抗氧化性。本文首次将贻贝启发化学和Michael加成反应相结合，采用生物相容性高分子（polyPEGMA）对SiO2纳米粒子进行表面改性，开发了一种简单、易操作、环境友好的方法。首先，通过使用稍微修改的Stober方法制备单分散SiO2 NPs。其次，用聚多巴胺（FDA）包覆SiO2纳米颗粒，聚多巴胺是通过多巴胺在碱性水溶液中的自聚合形成的。最后，以半胱胺盐酸盐为链转移剂，聚乙二醇甲基醚甲基丙烯酸酯为单体，通过链转移自由基聚合法合成了聚PEGMA，并将PDA包覆的SiO2纳米粒子与聚PEGMA偶联。通过透射电子显微镜、傅里叶变换红外光谱、热重分析和X射线光电子能谱等表征技术证实了这些复合材料的成功制备。该方法明显增强了SiO2纳米颗粒在不同有机溶剂和水溶液中的分散性。该合成方法简便、有效、环境友好，由于贻贝化学和链转移活性聚合的特点，也可推广到其他功能聚合物对SiO2纳米粒子的改性。(C)2015 Elsevier Ltd和Techna Group S.r.l. All rights reserved.
Silica nanoparticles (SiO2 NPs) have been widely applied in a number of domains because of their inodorous, non-pollution, optical transparency, chemical inert and good biocompatibility. However, to achieve better performance, surface modification of SiO2 NPs to enhance their dispersibility is generally required. In this paper, a simple, facile and environmental friendly procedure was developed for surface modification of SiO2 NPs with a biocompatible polymer (polyPEGMA) via combination of mussel inspired chemistry and Michael addition reaction for the first time. Firstly, monodisperse SiO2 NPs were prepared by using a slightly modified Stober process. Secondly, SiO2 NPs were coated with polydopamine (FDA), which was formed through self-polymerization of dopamine in an alkaline aqueous solution. Lastly, the PDA coated SiO2 NPs were facilely conjugated with polyPEGMA, which were synthesized through chain transfer free radical polymerization using cysteamine hydrochloride as chain transfer agent and poly(ethylene glycol) methyl ether methacrylate as the monomer. The successful preparation of these composites was confirmed by a number of characterization techniques including transmission electron microscopy, Fourier transform infrared spectroscopy, thermal gravimetric analysis and X-ray photoelectron spectroscopy. This method obviously enhance the dispersion of SiO2 NPs in different organic solvents and aqueous solution. This synthetic method is convenient, effective and environmental friendly, that can be also extended to modify SiO2 NPs with other functional polymers because of the features of mussel inspired chemistry and chain transfer living polymerization. (C) 2015 Elsevier Ltd and Techna Group S.r.l. All rights reserved.