Pediatric Fibromyalgia
Pediatric Fibromyalgia
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DOI：
10.1016/j.rdc.2009.06.001
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发表时间：
2009-05-01
影响因子：
2.3
通讯作者：
Buskila, Dan
中科院分区：
文献类型：
--
作者：
Buskila, Dan
纤维肌痛是一种特发性慢性疼痛综合征，以广泛的非关节肌肉骨骼疼痛和全身压痛点为特征。这种综合征与一系列症状有关，包括疲劳、睡眠不清爽、肠易激等。中枢神经系统敏感化是纤维肌痛的一个主要病理生理方面；此外，各种外部刺激，如创伤和应激，可能导致该综合征的发展。纤维肌痛最常见于中年，但可见于任何年龄段。本文综述了儿童纤维肌痛的流行病学、临床特点、病因、治疗和转归。
Fibromyalgia is an idiopathic chronic pain syndrome defined by widespread nonarticular musculoskeletal pain and generalized tender points. The syndrome is associated with a constellation of symptoms, including fatigue, nonrefreshing sleep, irritable bowel, and more. Central nervous system sensitization is a major pathophysiologic aspect of fibromyalgia; in addition, various external stimuli such as trauma and stress may contribute to development of the syndrome. Fibromyalgia is most common in midlife, but may be seen at any age. This article reviews the epidemiology, clinical characteristics, etiology, management, and outcome of pediatric fibromyalgia.