A complete backbone spectral assignment of lipid-free human apolipoprotein E (apoE).
A complete backbone spectral assignment of lipid-free human apolipoprotein E (apoE).
复制标题
无脂人载脂蛋白 E (apoE) 的完整主链光谱分配。
DOI：
10.1007/s12104-008-9122-8
复制
发表时间：
2008
影响因子：
0.9
通讯作者：
Wang,Jianjun
中科院分区：
文献类型：
--
作者：
Zhang,Yonghong;Chen,Jianglei;Wang,Jianjun
Apolipoprotein E is an exchangeable apolipoprotein that plays an important role in lipid/lipoprotein metabolism and cardiovascular diseases. Recent evidence indicates that apoE is also critical in several other important biological processes, including Alzheimer’s disease, cognitive function, immunoregulation, cell signaling and infectious diseases. Although the X-ray crystal structure of the apoE N-terminal domain was solved in 1991, there is no structure available for the apoE C-terminal domain and full-length apoE. Here we report a complete NMR backbone spectral assignment of lipid-free human apoE.
