Multimodal fusion with deep neural networks for leveraging CT imaging and electronic health record: a case-study in pulmonary embolism detection.
Multimodal fusion with deep neural networks for leveraging CT imaging and electronic health record: a case-study in pulmonary embolism detection.
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具有深层神经网络的多模式融合,用于利用CT成像和电子健康记录:肺栓塞检测的病例研究。
DOI:
10.1038/s41598-020-78888-w
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发表时间:
2020-12-17
影响因子:
4.6
通讯作者:
Lungren MP
中科院分区:
文献类型:
--
作者:
Huang SC;Pareek A;Zamanian R;Banerjee I;Lungren MP
Recent advancements in deep learning have led to a resurgence of medical imaging and Electronic Medical Record (EMR) models for a variety of applications, including clinical decision support, automated workflow triage, clinical prediction and more. However, very few models have been developed to integrate both clinical and imaging data, despite that in routine practice clinicians rely on EMR to provide context in medical imaging interpretation. In this study, we developed and compared different multimodal fusion model architectures that are capable of utilizing both pixel data from volumetric Computed Tomography Pulmonary Angiography scans and clinical patient data from the EMR to automatically classify Pulmonary Embolism (PE) cases. The best performing multimodality model is a late fusion model that achieves an AUROC of 0.947 [95% CI: 0.946–0.948] on the entire held-out test set, outperforming imaging-only and EMR-only single modality models.
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影响因子:
4.5
作者:
Banerjee I;Chen MC;Lungren MP;Rubin DL
通讯作者:
Rubin DL
影响因子:
8
作者:
Alonso-Martinez, J. L.;Anniccherico Sanchez, F. J.;Urbieta Echezarreta, M. A.
通讯作者:
Urbieta Echezarreta, M. A.
影响因子:
3.1
作者:
Chandra, Subani;Sarkar, Pralay K.;Cohen, Rubin I.
通讯作者:
Cohen, Rubin I.
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2.6
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Leslie, A;Jones, AJ;Goddard, PR
通讯作者:
Goddard, PR
影响因子:
7.5
作者:
Banerjee, Imon;Ling, Yuan;Lungren, Matthew P.
通讯作者:
Lungren, Matthew P.