MEA-Tools: an open source toolbox for the analysis of multi-electrode data with MATLAB
MEA-Tools: an open source toolbox for the analysis of multi-electrode data with MATLAB
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DOI：
10.1016/s0165-0270(02)00045-6
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发表时间：
2002-05-30
影响因子：
3
通讯作者：
Diesmann, M
中科院分区：
文献类型：
--
作者：
Egert, U;Knott, T;Diesmann, M
电生理学技术的最新进展创造了新的工具，用于采集和存储用许多电极同时记录的神经元活动。这些技术支持的功能，以及在周围的神经元或心脏网络的背景下，单个生电细胞的结构的分析。然而，用于分析这类数据的商业工具不容易适应新出现的数据分析和可视化要求，而且它们之间的交叉兼容性有限。在本报告中，我们介绍了一个免费的开源工具箱，称为微电极阵列工具（MEA工具），用于基于通用数据分析环境MATLAB（版本5.3-6.1，Mathworks，Natick，MA）分析多电极数据。工具箱本身是独立于平台的。文件接口目前支持在Microsoft Windows 95、98、NT和2000下使用MCRack（多通道系统，罗伊特林根，德国）记录的文件，但也可适用于其他数据采集系统。功能通过命令行输入和图形用户界面进行控制，并支持分析局部场电位、细胞外锋电位活动和连续记录的常见要求，以及通过其他仪器采集的补充数据。e，g.细胞内放大器数据可以被处理为连续记录或被触发到某个事件的时间窗口。(C)2002 Elsevier Science B. V.保留所有权利。
Recent advances in electrophysiological techniques have created new tools for the acquisition and storage of neuronal activity recorded simultaneously with numerous electrodes. These techniques support the analysis of the function as well as the structure of individual electrogenic cells in the context of surrounding neuronal or cardiac network. Commercially available tools for the analysis of such data, however, cannot be easily adapted to newly emerging requirements for data analysis and visualization, and cross compatibility between them is limited. In this report we introduce a free open source toolbox called microelectrode array tools (MEA-Tools) for the analysis of multi-electrode data based on the common data analysis environment MATLAB (version 5.3-6.1, The Mathworks, Natick, MA). The toolbox itself is platform independent. The file interface currently supports files recorded with MCRack (Multi Channel Systems, Reutlingen, Germany) under Microsoft Windows 95, 98, NT, and 2000, but can be adapted to other data acquisition systems. Functions are controlled via command line input and graphical user interfaces, and support common requirements for the analysis of local field potentials, extracellular spike activity, and continuous recordings, in addition to supplementary data acquired by additional instruments. e,g. intracellular amplifiers. Data may be processed as continuous recordings or time windows triggered to some event. (C) 2002 Elsevier Science B.V. All rights reserved.