Vitamin D deficiency in the intensive care unit: an invisible accomplice to morbidity and mortality?

Vitamin D deficiency in the intensive care unit: an invisible accomplice to morbidity and mortality?
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DOI:
10.1007/s00134-009-1642-x
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发表时间:
2009-12-01
影响因子:
38.9
通讯作者:
Center, Jacqueline R.
Center, Jacqueline R.
中科院分区:
医学1区
文献类型:
--
作者:
Lee, Paul;Nair, Priya;Center, Jacqueline R.

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维生素D缺乏症与慢性疾病之间的联系是众所周知的。维生素D缺乏与一般人群死亡率的增加有关。尽管有这些知识,但在重症监护的危重患者中,维生素D不足很少被考虑,也很少被充分替代。我们提出了一个假设模型,证明维生素D缺乏可能是一个未被认识到的贡献者在重症监护患者的不良后果。
The association between vitamin D deficiency and chronic illness is well-known. Vitamin D deficiency has been associated with increased mortality in the general population. Despite this knowledge, vitamin D insufficiency is seldom considered and rarely replaced adequately, if at all, in critically ill patients in intensive care. We present a hypothetic model demonstrating how vitamin D deficiency may be an unrecognized contributor to adverse outcome in intensive care patients.