RHINOVIRUS INFECTIONS IN TECUMSEH, MICHIGAN - FREQUENCY OF ILLNESS AND NUMBER OF SEROTYPES
RHINOVIRUS INFECTIONS IN TECUMSEH, MICHIGAN - FREQUENCY OF ILLNESS AND NUMBER OF SEROTYPES
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DOI：
10.1093/infdis/156.1.43
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发表时间：
1987-07-01
影响因子：
6.4
通讯作者：
OHMIT, S
中科院分区：
文献类型：
--
作者：
MONTO, AS;BRYAN, ER;OHMIT, S
我们研究了1976年至1981年密歇根州特库姆塞社区居民中鼻病毒相关疾病，这是1966年至1971年类似研究的延续。鼻病毒是所有年龄组（包括幼儿）中最常见的呼吸道病原体。年龄别隔离率的模式与总呼吸道疾病的模式相似。与鼻病毒相关的疾病一般较轻，但持续时间相对较长;经常限制日常活动，特别是在某些年龄组。所有分离株的分型工作已经完成;使用高质量的抗血清，几乎可以对所有分离株进行分型。因此，新的血清型可能不会进化，并且大多数已经被鉴定。不同血清型的出现频率差异很明显，但根据现有数据很难按重要性排序。
We studied rhinovirus-associated illnesses from 1976 to 1981 among residents of the community of Tecumseh, Michigan, in a continuation of similar studies done in 1966-1971. Rhinoviruses were the most frequently isolated respiratory pathogen in all age groups, including young children. The pattern of age-specific isolation rates was similar to that for total respiratory illness. Rhinovirus-associated illnesses were generally mild but of relatively long duration; restriction of daily activity was frequent, especially in certain age groups. Typing of all isolates has been completed; with high-quality antisera nearly all isolates could be typed. Thus, new serotypes are probably not evolving, and most have already been identified. Differences in frequency of occurrences of different serotypes were evident, but ranking in order of importance was difficult based on existing data.