REDUCED VITAL CAPACITY IN ELDERLY PERSONS WITH HYPERTENSION, CORONARY-HEART-DISEASE, OR LEFT-VENTRICULAR HYPERTROPHY - THE CARDIOVASCULAR HEALTH STUDY
REDUCED VITAL CAPACITY IN ELDERLY PERSONS WITH HYPERTENSION, CORONARY-HEART-DISEASE, OR LEFT-VENTRICULAR HYPERTROPHY - THE CARDIOVASCULAR HEALTH STUDY
复制标题
DOI：
10.1378/chest.107.1.28
复制
发表时间：
1995-01-01
期刊：
影响因子：
9.6
通讯作者：
MANOLIO, TA
中科院分区：
文献类型：
--
作者：
ENRIGHT, PL;KRONMAL, RA;MANOLIO, TA
心血管健康研究提供了在老年人人群样本中确定亚临床和临床心血管疾病与肺功能相关性的机会。包括2，955名女性和2，246名男性，年龄超过64岁，他们从四个社区招募参加这项观察性研究，并完成了广泛的检查，包括肺功能测定，超声心动图和血压。目前吸烟者、吸烟量>20包年的既往吸烟者以及有哮喘、慢性支气管炎或肺气肿病史的人被排除在该分析之外，留下2，784人（55%）。收缩性高血压或冠状动脉疾病与FEV（1）下降40- 100-mL和FVC下降50- 150-mL相关，而充血性心力衰竭病史与FEV（1）和FVC下降200 - 300 mL相关（p
The Cardiovascular Health Study provided the opportunity to determine the association of subclinical and clinical cardiovascular disease with pulmonary function in a population sample of elderly adults. Included were 2,955 women and 2,246 men over age 64 years who were recruited for this observational study from four communities and completed extensive examinations that included spirometry, echocardiograms, and blood pressure. Current smokers, past smokers with >20 pack-years of smoking, and persons with a history of asthma, chronic bronchitis, or emphysema were excluded from this analysis, leaving 2,784 (55%) of the cohort. Systolic hypertension or coronary artery disease was associated with 40- to 100-mL decrements in FEV(1) and 50- to 150-mL decrements in FVC, while a history of congestive heart failure was associated with 200 to 300 mL lower FEV(1) and FVC values (p