NO DETECTION OF ENTAMOEBA HISTOLYTICA BY MULTIPLEX POLYMERASE CHAIN REACTION IN CHILDREN WITH ACUTE NON-BLOODY DIARRHEA IN GUATEMALA
NO DETECTION OF ENTAMOEBA HISTOLYTICA BY MULTIPLEX POLYMERASE CHAIN REACTION IN CHILDREN WITH ACUTE NON-BLOODY DIARRHEA IN GUATEMALA
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DOI：
10.1097/inf.0000000000001756
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发表时间：
2018-04-01
影响因子：
3.6
通讯作者：
Gaensbauer, James
中科院分区：
文献类型：
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作者：
Kamidani, Satoshi;Melgar, Mario;Gaensbauer, James
溶组织内阿米巴被认为是儿科非血性腹泻的普遍原因。使用多重聚合酶链反应检测，我们确定了298例危地马拉儿童急性，非血性腹泻的粪便病原体。尽管总体病原体负担很高，但我们没有发现大肠杆菌病例。溶组织剂了解当地流行病学对E.低收入环境中的溶组织治疗策略。
Entamoeba histolytica is believed to be a ubiquitous cause of pediatric non-bloody diarrhea. Using a multiplex polymerase chain reaction assay, we identified stool pathogens in 298 Guatemalan children presenting with acute, non-bloody diarrhea. Despite a high overall pathogen burden, we identified no cases of E. histolytica. Knowledge of local epidemiology is important to inform E. histolytica therapeutic strategies in low-income settings.