Spatial response properties of homing pigeon hippocampal neurons: correlations with goal locations, movement between goals, and environmental context in a radial-arm arena
Spatial response properties of homing pigeon hippocampal neurons: correlations with goal locations, movement between goals, and environmental context in a radial-arm arena
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DOI：
10.1007/s00359-004-0562-z
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发表时间：
2004-12-01
影响因子：
2.1
通讯作者：
Bingman, VP
中科院分区：
文献类型：
--
作者：
Hough, GE;Bingman, VP
海马结构在环境空间的神经表征中起着进化保守的作用。然而，空间生态学中的物种差异培养了海马神经元如何代表空间的物种差异的期望。为了确定信鸽HF神经元的空间响应特性，我们记录了鸟类自由航行的径向竞技场在四个目标位置寻找食物的孤立单位。76个神经元中有50个表现出放电率的变化，可以分为三个反应类别。位置细胞（n=25）在竞技场空间的受限位置显示出更高的放电率，通常靠近目标位置。路径细胞（n=13）显示较高的射击率作为鸽子之间的一个子集的目标位置移动。当鸽子在基线保持空间时，与在竞技场内相比，竞技场关闭细胞（n=12）更活跃。总的来说，记录的神经元的可靠性和一致性得分较低，大鼠的位置细胞。鸽子海马结构神经元的空间反应曲线的差异，当与大鼠相比，提供了一个出发点，更好地理解空间行为和海马结构神经元如何参与空间的代表之间的关系。
The amniote hippocampal formation plays an evolutionarily-conserved role in the neural representation of environmental space. However, species differences in spatial ecology nurture the expectation of species differences in how hippocampal neurons represent space. To determine the spatial response properties of homing pigeon (Columba livia) HFneurons, we recorded from isolated units in birds freely navigating a radial arena in search of food present at four goal locations. Fifty of 76 neurons displayed firing rate variations that could be placed into three response categories. Location cells (n=25) displayed higher firing rates at restricted locations in the arena space, often in proximity to goal locations. Path cells (n=13) displayed higher firing rates as a pigeon moved between a subset of goal locations. Arena-off cells (n=12) were more active when a pigeon was in a baseline holding space compared to inside the arena. Overall, reliability and coherence scores of the recorded neurons were lower compared to rat place cells. The differences in the spatial response profiles of pigeon hippocampal formation neurons, when compared to rats, provide a departure point for better understanding the relationship between spatial behavior and how hippocampal formation neurons participate in the representation of space.