Epidemiology of Helicobacter pylori infection and public health implications.
Epidemiology of Helicobacter pylori infection and public health implications.
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DOI：
10.1111/j.1523-5378.2011.00874.x
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发表时间：
2011-09
期刊：
影响因子：
4.4
通讯作者：
Yamaoka Y
中科院分区：
文献类型：
--
作者：
Goh KL;Chan WK;Shiota S;Yamaoka Y
本文综述了2010年4月至2011年3月发表在同行评议期刊上的幽门螺杆菌流行病学和公共卫生影响的研究。不同地理区域和族裔群体之间的流行率差别很大。一项来自美国的有趣的研究将非洲血统的程度确定为H。幽门感染两项研究表明，幼儿期是感染的传播期，并确定受感染的兄弟姐妹是一个重要的风险因素。经口传播的途径已被证实与几项研究表明H。口腔中的幽门螺杆菌。研究表明，H。pylori感染的作用以及生活条件差和卫生条件差在H.幽门螺杆菌感染，支持口腔-粪便传播途径。筛选H. pylori作为胃癌的预筛选策略在日本已有报道，而H.根除幽门螺杆菌作为胃癌预防策略，现在已在日本指南中得到进一步强调。两项研究表明，在消化不良和消化性溃疡疾病的负担与H。根除幽门
This review summarizes studies on the epidemiology and public health implications of Helicobacter pylori published in peer-reviewed journals from April 2010 through March 2011. Prevalence rates vary widely between different geographical regions and ethnic groups. An interesting study from the USA identified the degree of African ancestry as an independent predictor of H. pylori infection. Two studies have demonstrated early childhood as the period of transmission of infection and identified an infected sibling as an important risk factor. An oral–oral route of spread has been substantiated with several studies showing the presence of H. pylori in the oral cavity. Studies have shown the presence of H. pylori in drinking water and the role of poor living conditions and sanitation in H. pylori infection, supporting an oral–fecal route of spread. Screening for H. pylori as a gastric cancer prescreening strategy has been described in Japan, and the importance of H. pylori eradication as a gastric cancer–prevention strategy has now been further emphasized in Japanese guidelines. Two studies have shown a decrease in the burden of dyspepsia and peptic ulcer disease with H. pylori eradication.