Neurite outgrowth and selection of new electrical connections by adult Helisoma neurons.

Neurite outgrowth and selection of new electrical connections by adult Helisoma neurons.
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神经突的生长和成年 Helisoma 神经元对新电连接的选择。

DOI:
10.1152/jn.1982.48.2.569
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发表时间:
1982
影响因子:
2.5
通讯作者:
Kater,SB
Kater,SB
中科院分区:
医学3区
文献类型:
--
作者:
Bulloch,AG;Kater,SB

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6.新的,稳定的,和短暂的连接的细胞基础进行了比较,以现存的连接,通过检查他们的易失性解偶联低pH值的盐水(pH值5.3至0.1)。通过这种处理,5-5和5-4连接都被解偶联到与现存连接相同的程度,这表明了共同的生理基础。7.它的结论是,神经元5表现出高度的特异性,在建立瞬态和稳定的电连接。新的连接在生理上与现存的连接无法区分,并且是由于新生长的中央神经突即使在存在中断或外来地形的情况下也表现出定位目标的非凡能力。
6. The cellular basis of the new, stable, and transient connections was compared to an extant connection by examining their susceptability to uncoupling by low-pH saline (pH 5.3 t 0.1). Both the 5-5 and 5-4 connections were uncoupled by this treatment to the same degree as the extant connection, suggesting a common physiological basis. 7. It is concluded that neuron 5 exhibits a high degree of specificity in establishing both transient and stable electrical connections. The new connections are physiologically indistinguishable from an extant connection and are due to newly grown central neurites that exhibit a remarkable ability to locate targets even in the presence of disrupted or foreign terrain.