C- and Adelta-fibre mediated thermal perception: response to rate of temperature change using method of limits.
C- and Adelta-fibre mediated thermal perception: response to rate of temperature change using method of limits.
复制标题
C 纤维和 Adelta 纤维介导的热感知：使用极限方法对温度变化率的响应。
DOI：
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发表时间：
2000
影响因子：
0.9
通讯作者：
J. Ravey
中科院分区：
文献类型：
--
作者：
S. Palmer;Denis. Martin;W. Steedman;J. Ravey
调查温度变化率对热阈值影响的研究使用了多种不同的方法和阈值组合，其中许多显示统计分析报告不完整。有人建议，C-和Adelta-纤维介导的阈值不同，在他们的反应不同的温度变化率。10名健康女性志愿者（年龄18-26岁;平均21 +/- S.D. 2.53）在优势手大鱼际隆起上进行冷觉（CS）、温热觉（WS）、冷痛（CP）和热痛（HP）阈值测定。使用0.5、1、2.5和4 ℃/s的温度变化速率，并采用改进的极限方法。适应温度为32 ℃，热电极尺寸为3cm × 3cm。结果显示WS、HP和CP阈值随着温度变化率的增加而显著增加（所有p < 0.001），但CS没有显著变化（p = 0.653）。这些结果表明，阈值与C-纤维组件（WS，HP和CP）和Adelta纤维介导的（CS）表现不同。单独对测量伪影的传统解释不足以合理化这些结果，可能涉及其他因素。缓慢的温度变化率被证明可以减少记录阈值的平均个体内差异，并且还可以消除HP阈值测定的天花板效应。因此，在临床上，使用缓慢的温度变化速率和极限方法具有一系列好处，不仅仅是最小化测量伪影。
Studies investigating the effect of rate of temperature change on thermal thresholds have used a variety of different methods and threshold combinations, and many display incomplete reporting of statistical analyses. It has been suggested that C- and Adelta-fibre mediated thresholds differ in their reaction to different rates of temperature change. Ten healthy female volunteers (aged 18-26 years; mean 21 +/- S.D. 2.53) undertook cold sensation (CS), warm sensation (WS), cold pain (CP) and heat pain (HP) threshold determinations on the thenar eminence of the dominant hand. Rates of temperature change of 0.5, 1, 2.5 and 4 degrees C/s were used, with a modified method of limits. Adaptation temperature was 32 degrees C and thermode size 3 cm x 3 cm. Results showed a significant increase in WS, HP and CP thresholds with increased rates of temperature change (all p < 0.001), but no significant change for CS (p = 0.653). These results suggest that thresholds with a C-fibre component (WS, HP and CP) and those that are Adelta-fibre mediated (CS) behave differently. A traditional explanation of measurement artefact alone is insufficient in rationalizing these results, with additional factors potentially involved. Slow rates of temperature change were shown to reduce mean intra-individual differences in recorded threshold values, and also to abolish ceiling effects with HP threshold determinations. Clinically, therefore, using slow rates of temperature change with method of limits has a range of benefits over and above simply minimizing measurement artefact.
影响因子：
14.5
作者：
YARNITSKY, D;OCHOA, JL
通讯作者：
OCHOA, JL
影响因子：
2.5
作者：
Vierck, CJ;Cannon, RL;Whitsel, BL
通讯作者：
Whitsel, BL