Comparative plasma catecholamine and hemodynamic responses to handgrip, cold pressor and supine bicycle exercise testing in normal subjects.
Comparative plasma catecholamine and hemodynamic responses to handgrip, cold pressor and supine bicycle exercise testing in normal subjects.
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正常受试者对握力、冷加压和仰卧自行车运动测试的血浆儿茶酚胺和血流动力学反应的比较。
DOI：
10.1016/s0735-1097(83)80381-7
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发表时间：
1983
影响因子：
24
通讯作者：
James L. Ritchie
中科院分区：
文献类型：
--
作者：
John R. Stratton;Jeffrey B. Halter;Al Hallstrom;James H. Caldwell;James L. Ritchie
比较了10名健康男性（27 ± 3岁）（± 1个标准差）在症状限制性握手（33%最大自主收缩，持续4.4 ± 1.8分钟）、冷加压测试（6分钟）和症状限制性仰卧自行车运动（22 ± 5分钟）期间的一系列血流动力学和血浆儿茶酚胺反应。血浆儿茶酚胺浓度测定放射酶法，射血分数和心脏容积的变化进行了评估，平衡放射性核素血管造影。在最大仰卧位运动期间，血浆去甲肾上腺素和肾上腺素浓度增加3至6倍以上，无论是在限制性握力或冷加压试验。此外，心率、收缩压、心率-血压乘积、每搏输出量、射血分数和心输出量的增加在自行车运动期间显著大于其他两项测试。在冷加压试验的前2分钟，射血分数下降0.05单位或更多在年轻的正常人中是常见的（6/10例）或限制性握力（3/10例），但在最大仰卧蹬车运动中从未发生。更一致，并与更高的交感神经系统激活相关，使其成为一种可能比握力运动或冷加压试验更有用的诊断应激。
Serial hemodynamic and plasma catecholamine responses were compared among 10 healthy men (27 ± 3 years) ( ± 1 standard deviation) during symptom-limited handgrip (33% maximal voluntary contraction for 4.4 ± 1.8 minutes), cold pressor testing (6 minutes) and symptom-limited supine bicycle exercise (22 ± 5 minutes). Plasma catecholamine concentrations were measured by radioenzymatic assays; ejection fraction and changes in cardiac volumes were assessed by equilibrium radionuclide angiography. During maximal supine exercise, plasma norepinephrine and epinephrine concentrations increased three to six times more than during either symptom-limited handgrip or cold pressor testing. Additionally, increases in heart rate, systolic blood pressure, rate-pressure product, stroke volume, ejection fraction and cardiac output were significantly greater during bicycle exercise than during the other two tests. A decrease in ejection fraction of 0.05 units or more was common in young normal subjects during the first 2 minutes of cold pressor testing (6 of 10 subjects) or at symptom-limited handgrip (3 of 10), but never occurred during maximal supine bicycle exercise.The magnitude of hemodynamic changes with maximal supine bicycle exercise was greater, more consistent and associated with much higher sympathetic nervous system activation, making this a potentially more useful diagnostic stress than either handgrip exercise or cold pressor testing.
小肌肉群静态和动态运动的血流动力学反应的相似性。
影响因子：
20.1
作者：
Blomqvist,CG;Lewis,SF;Taylor,WF;Graham,RM
通讯作者：
Graham,RM
等长握力和动态运动对左心室功能的影响。
DOI：
--
发表时间：
1980
期刊：
Journal of nuclear medicine : official publication, Society of Nuclear Medicine
影响因子：
--
作者：
Peter,CA;Jones,RH
通讯作者：
Jones,RH
平衡放射性核素心室造影检测和评估冠状动脉疾病程度的直立和仰卧自行车运动的比较。
影响因子：
4.8
作者：
Freeman,MR;Berman,DS;Staniloff,H;Elkayam,U;Maddahi,J;Swan,HJ;Forrester,J
通讯作者：
Forrester,J