Phase behavior of dipalmitoylphosphatidylglycerol bilayer membrane in saline water under high pressure
Phase behavior of dipalmitoylphosphatidylglycerol bilayer membrane in saline water under high pressure
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二棕榈酰磷脂酰甘油双层膜在高压盐水中的相行为
DOI：
10.1142/s2010194512004059
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发表时间：
2012
期刊：
影响因子：
--
通讯作者：
S. Tanaka et al.
中科院分区：
文献类型：
--
作者：
N. Tamai;et al;S. Tanaka et al.
用光学方法观察了双棕榈酰磷脂酰甘油(DPPG)双层膜在常压和高压下在氯化钠水溶液中的相变。DPPG双层膜的温度-压力相图表明，DPPG双层膜的相行为与二棕榈酰磷脂酰胆碱(DPPC)双层膜相似，但存在交错的凝胶(LβI)相。将相图与在磷酸盐缓冲液中得到的相图进行比较，发现盐对极性头基团间排斥作用的屏蔽作用抑制了LβI相的形成。
The phase transitions of dipalmitoylphosphatidylglycerol (DPPG) bilayer membrane in the aqueous NaCl solution were observed by means of an optical method under atmospheric and high pressures. The temperature-pressure phase diagram of the DPPG bilayer showed that the phase behavior of the DPPG bilayer was similar to that of dipalmitoylphosphatidylcholine (DPPC) bilayer except for the interdigitated gel (LβI) phase. Comparing the phase diagram with the diagram obtained in a phosphate buffer, it turned out that the formation of the LβI phase is suppressed by the shielding effect of NaCl on the repulsive interaction among polar headgroups.