Clinical characteristics of older patients infected with COVID-19: A descriptive study.
Clinical characteristics of older patients infected with COVID-19: A descriptive study.
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DOI：
10.1016/j.archger.2020.104058
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发表时间：
2020-07-01
影响因子：
4
通讯作者：
Zhang, Jinjun
中科院分区：
文献类型：
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作者：
Niu, Shengmei;Tian, Sijia;Zhang, Jinjun
自二零一九年新型冠状病毒（COVID-19）爆发以来，其在全球迅速蔓延。人群对COVID-19易感，老年人比年轻人更容易患各种疾病，包括COVID-19感染毫无疑问。方法：收集2020年1月20日至2月29日北京市急救中心转运至定点医院的确诊老年患者资料，分析老年患者的流行病学和临床特征。这些信息包括人口统计学、流行病学、临床、严重程度分类和结局。所有病例分为三组，并比较50-64岁、65-79岁和80岁以上年龄组的差异。结果：56. 7%的老年确诊患者为男性，发热（78. 3%）、咳嗽（56. 7%）、呼吸困难（30. 0%）和乏力（23. 3%）是COVID-19感染的常见症状。3组患者严重程度分级比较差异有统计学意义，80岁以上组与中年组、65-79岁组比较差异有统计学意义。截至2月29日，38.3%的患者已出院，53.3%的患者仍在住院，老年人COVID-19感染的病死率为8.3%。结论：COVID-19感染普遍易感，老年患者病死率相对较高，应引起更多关注。
OBJECTIVES: Since the outbreak of 2019 novel coronavirus (COVID-19), which has spread in the world rapidly. Population have a susceptibility to COVID-19, older people were more susceptible to have a variety diseases than younger, including COVID-19 infection with no doubt. This study focused on older patients with COVID-19 infection and analyzed the epidemiological and clinical characteristics of them.METHODS: We collected information on confirmed older patient transferred by Beijing Emergency Medical Service (EMS) to the designated hospitals from Jan 20 to Feb 29, 2020. The information including demographic, epidemiological, clinical, classification of severity and outcomes. All cases were categorized into three groups and compared the difference between aged 50-64 years, 65-79 years and older than 80 years.RESULTS: 56.7 % of elderly confirmed patients were male, fever (78.3 %), cough (56.7 %), dyspnea (30.0 %), and fatigue (23.3 %) were common symptoms of COVID-19 infection. Classification of severity has statistically significant differences between the three groups, compared with middle-aged patients and aged 65-79 years group, older than 80 years group had significant statistical differences in contacted to symptomatic case in 14 days. As of Feb 29, 38.3 % patients had discharged and 53.3 % patients remained in hospital in our study, the fatality of COVID-19 infection in elderly was 8.3 %.CONCLUSIONS: The COVID-19 infection is generally susceptible with a relatively high fatality rate in older patients, we should pay more attention to the elderly patients with COVID-19 infection.