The assessment of transmission efficiency and latent infection period in asymptomatic carriers of SARS-CoV-2 infection
The assessment of transmission efficiency and latent infection period in asymptomatic carriers of SARS-CoV-2 infection
复制标题
DOI：
10.1016/j.ijid.2020.06.036
复制
发表时间：
2020-10-01
影响因子：
8.4
通讯作者：
Wu, Jiabing
中科院分区：
文献类型：
--
作者：
Liu, Zhirong;Chu, Ruilin;Wu, Jiabing
很少有研究关注SARS-CoV-2无症状感染者的传播效率。我们对安徽省147名无症状感染者进行了随访研究。其中男性50.0%，40岁以上50.3%，农民43.8%，皖北地区68.7%。147例无症状感染者中有16例在隔离观察后14天出现症状，经诊断为确诊病例。发现可能的潜伏感染期为发病前1-5天，中位时间为2天。16例无症状感染者转移的确诊病例第二次发病率为9.7%（23/236名密切接触者），131例无症状感染者第二次发病率为2.6%（24/914名密切接触者），两组间第二次发病率差异有统计学意义(p
Few studies have focused on the transmission efficiency of asymptomatic carriers of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Our follow-up study was performed on 147 asymptomatic carriers in Anhui Province. Of these, 50.0% were male, 50.3% were older than 40 years, 43.8% were farmers, and 68.7% were from the north of Anhui Province. 16 of the 147 asymptomatic carriers developed symptoms in the following 14 days of isolated observation, and were subsequently diagnosed as confirmed cases. The possible latent infection period was found to range from 1-5 days before onset, with a median time of 2 days. The second attack rate for the 16 confirmed cases who had transferred from being asymptomatic carriers was 9.7% (23/236 close contacts), while for the 131 asymptomatic carriers the rate was 2.6% (24/914 close contacts), showing a significant difference in second attack rate between the two groups (p