A CHRONOLOGICAL STUDY OF HISTOPATHOLOGY OF FILARIAL DISEASE IN CATS AND DOGS CAUSED BY BRUGIA PAHANGI (BUCKLEY AND EDESON 1956)
A CHRONOLOGICAL STUDY OF HISTOPATHOLOGY OF FILARIAL DISEASE IN CATS AND DOGS CAUSED BY BRUGIA PAHANGI (BUCKLEY AND EDESON 1956)
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DOI：
10.1016/0035-9203(67)90162-9
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发表时间：
1967-01-01
影响因子：
2.2
通讯作者：
SAHYOUN, PF
中科院分区：
文献类型：
--
作者：
SCHACHER, JF;SAHYOUN, PF
已通过 H 和 E 染色的连续切片（间隔 3 天至 16 1/2 个月）研究了猫淋巴结中的 B. pihangi 感染；还检查了几只狗的材料。病理变化与药剂的生命周期相关进行描述和讨论。发现反应：活的和死的幼虫（第三和第四阶段）；第三次和第四次蜕皮的蜕皮液和蜕皮角质层；子宫分泌物、未受精卵和微丝蚴；最后是活的和死的成虫。狗的病理变化比猫明显更快、更极端。讨论了丝虫病某些特征的基本因果机制，涉及丝虫生命周期、蠕虫及其产物产生的病变、淋巴引流模式以及淋巴系统的功能生理学。
B. pihangi infections in the lymph nodes of cats have been studied in serial sections stained with H and E at intervals of from 3 days to 16 1/2 months; material from a few dogs was also examined. The pathological changes are described and discussed in relation to the life cycle of the agent. Reactions were found to: living and dead larvae (3rd and 4th stage); moulting fluids and moulted cuticles of the 3rd and 4th moults; uterine secretions, infertile eggs and microfilariae; and finally to living and dead adult worms. Pathological changes in dogs are strikingly more rapid and extreme than in cats. Basic causal mechanisms underlying some features of filarial disease are discussed in relation to the filarial life cycle, the lesions produced by worms and their products, the pattern of lymphatic drainage, and the functional physiology of the lymphatic system.