Endothelial progenitor cell mobilization following acute wound injury.

Endothelial progenitor cell mobilization following acute wound injury.
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急性伤口损伤后内皮祖细胞动员。

DOI:
10.1111/wrr.12097
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发表时间:
2013
期刊:
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society
影响因子:
--
通讯作者:
Thom,StephenR
Thom,StephenR
中科院分区:
--
文献类型:
--
作者:
Fukaya,Eri;Margolis,DavidJ;Miller,ChristopherJ;Milovanova,TatyanaN;Papadopoulos,Maryte;Thom,StephenR

文献摘要

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Endothelial progenitor cells (EPC) are essential for neovascularization and tissue repair. Asahara et al1 first described EPCs as cells isolated from human peripheral blood based on cell surface antigen expression and their ability to differentiate in vitro into endothelial cells (EC) 1. Prior to this discovery, vasculogenesis was thought to occur only in the fetal environment and angiogenesis, the sprouting of new vessels from existing vasculature, was the only form of neovascularization.