"Switch-Off" of Respiratory Sinus Arrhythmia Can Occur in a Minority of Subjects During Functional Magnetic Resonance Imaging (fMRI)
"Switch-Off" of Respiratory Sinus Arrhythmia Can Occur in a Minority of Subjects During Functional Magnetic Resonance Imaging (fMRI)
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DOI：
10.3389/fphys.2018.01688
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发表时间：
2018-11-27
影响因子：
4
通讯作者：
Pfurtscheller, Gert
中科院分区：
文献类型：
--
作者：
Ressler, Beate;Schwerdtfeger, Andreas;Pfurtscheller, Gert
一组23名健康的扫描仪幼稚参与者的功能性磁共振成像（fMRI）研究与增加状态焦虑表现出0.1 Hz的振荡血氧水平依赖（BOLD）信号，心率（HR）心跳间隔（RRI）和呼吸。本文的目的是探索呼吸和RRI的慢振荡和他们的相位耦合应用动态“逐波”分析。5名具有高或中等水平fMRI相关焦虑的参与者（年龄23.8 ± 3.3岁）在5分钟静息状态下至少有一个连续呼吸波，呼吸频率在6至9次呼吸/分钟之间。结果表明：（1）主频率为0.1Hz和0.15Hz的呼吸振荡与RRI呈1：1的耦合关系; (ii)吸气时间明显长于呼气时间。(iii)RRI最小值（HR开始降低）与吸气早期一致，RRI最大值（HR开始升高）与吸气晚期一致。(iv)RRI节律领先于呼吸节律。这种相位耦合模式与典型的呼吸性窦性心律失常完全相反，在典型的呼吸性窦性心律失常中，HR在吸气期间增加，在呼气期间降低。
A group of 23 healthy scanner naive participants of a functional magnetic resonance imaging (fMRI) study with increased state anxiety exhibited 0.1 Hz oscillations in blood oxygenation-level-dependent (BOLD) signals, heart rate (HR) beat-to-beat intervals (RRI) and respiration. The goal of the present paper is to explore slow oscillations in respiration and RRI and their phase-coupling by applying the dynamic "wave-by-wave" analysis. Five participants with either high or moderate levels of fMRI-related anxiety (age 23.8 +/- 3.3y) were found with at least one bulk of consecutive breathing waves with a respiration rate between 6 to 9 breaths/min in a 5-min resting state. The following results were obtained: (i) Breathing oscillations with dominant frequencies at 0.1 Hz and 0.15 Hz displayed a 1 : 1 coupling with RRI. (ii) Inspiration time was significantly longer than expiration time. (iii) RRI minima (start of HR decrease) coincided with the early inspiration, and RRI maxima (start of HR increase) coincided with the late inspiration. (iv) RRI rhythm led over the respiratory rhythm. This phase-coupling pattern is quite contrary to typical respiratory sinus arrhythmia where HR increases during inspiration and decreases during expiration.